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Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells

Overview of attention for article published in Cell & Bioscience, March 2015
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Mentioned by

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1 tweeter

Citations

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9 Dimensions

Readers on

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19 Mendeley
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Title
Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells
Published in
Cell & Bioscience, March 2015
DOI 10.1186/s13578-015-0001-6
Pubmed ID
Authors

Jinfeng Suo, Daniel Medina, Sabrina Herrera, Ze-Yi Zheng, Lei Jin, Gary C Chamness, Alejandro Contreras, Carolina Gutierrez, Susan Hilsenbeck, Arzu Umar, John A Foekens, Samir Hanash, Rachel Schiff, Xiang H-F Zhang, Eric C Chang

Abstract

The INT6 gene was first discovered as a site of integration in mouse mammary tumors by the mouse mammary tumor virus; however, INT6's role in the development of human breast cancer remains largely unknown. By gene silencing, we have previously shown that repressing INT6 promotes transforming activity in untransformed human mammary epithelial cells. In the present study, guided by microarray data of human tumors, we have discovered a role of Int6 in stromal fibroblasts.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 32%
Student > Ph. D. Student 5 26%
Student > Master 1 5%
Student > Bachelor 1 5%
Student > Doctoral Student 1 5%
Other 2 11%
Unknown 3 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 32%
Medicine and Dentistry 3 16%
Psychology 2 11%
Agricultural and Biological Sciences 2 11%
Immunology and Microbiology 1 5%
Other 2 11%
Unknown 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2015.
All research outputs
#2,591,404
of 4,883,853 outputs
Outputs from Cell & Bioscience
#61
of 128 outputs
Outputs of similar age
#86,488
of 152,446 outputs
Outputs of similar age from Cell & Bioscience
#4
of 5 outputs
Altmetric has tracked 4,883,853 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 128 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 152,446 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.