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Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells

Overview of attention for article published in Cell & Bioscience, March 2015
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1 X user

Citations

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9 Dimensions

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20 Mendeley
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Title
Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells
Published in
Cell & Bioscience, March 2015
DOI 10.1186/s13578-015-0001-6
Pubmed ID
Authors

Jinfeng Suo, Daniel Medina, Sabrina Herrera, Ze-Yi Zheng, Lei Jin, Gary C Chamness, Alejandro Contreras, Carolina Gutierrez, Susan Hilsenbeck, Arzu Umar, John A Foekens, Samir Hanash, Rachel Schiff, Xiang H-F Zhang, Eric C Chang

Abstract

The INT6 gene was first discovered as a site of integration in mouse mammary tumors by the mouse mammary tumor virus; however, INT6's role in the development of human breast cancer remains largely unknown. By gene silencing, we have previously shown that repressing INT6 promotes transforming activity in untransformed human mammary epithelial cells. In the present study, guided by microarray data of human tumors, we have discovered a role of Int6 in stromal fibroblasts.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 35%
Student > Ph. D. Student 4 20%
Student > Master 2 10%
Student > Doctoral Student 1 5%
Student > Bachelor 1 5%
Other 2 10%
Unknown 3 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 30%
Agricultural and Biological Sciences 3 15%
Medicine and Dentistry 3 15%
Psychology 2 10%
Immunology and Microbiology 1 5%
Other 2 10%
Unknown 3 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2015.
All research outputs
#15,327,280
of 22,796,179 outputs
Outputs from Cell & Bioscience
#395
of 927 outputs
Outputs of similar age
#153,674
of 258,843 outputs
Outputs of similar age from Cell & Bioscience
#5
of 10 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 927 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,843 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.