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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Attenuation of acute stroke injury in rat brain by minocycline promotes blood–brain barrier remodeling and alternative microglia/macrophage activation during recovery
|
|---|---|
| Published in |
Journal of Neuroinflammation, January 2015
|
| DOI | 10.1186/s12974-015-0245-4 |
| Pubmed ID | |
| Authors |
Yirong Yang, Victor M Salayandia, Jeffrey F Thompson, Lisa Y Yang, Eduardo Y Estrada, Yi Yang |
| Abstract |
Minocycline reduces reperfusion injury by inhibiting matrix metalloproteinases (MMPs) and microglia activity after cerebral ischemia. Prior studies of minocycline investigated short-term neuroprotective effects during subacute stage of stroke; however, the late effects of minocycline against early reperfusion injury on neurovascular remodeling are less well studied. We have shown that spontaneous angiogenesis vessels in ischemic brain regions have high blood-brain barrier (BBB) permeability due to lack of major tight junction proteins (TJPs) in endothelial cells at three weeks. In the present study, we longitudinally investigated neurological outcome, neurovascular remodeling and microglia/macrophage alternative activation after spontaneous and minocycline-induced stroke recovery. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| Netherlands | 1 | <1% |
| Unknown | 151 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 25% |
| Researcher | 23 | 15% |
| Student > Bachelor | 19 | 12% |
| Student > Master | 12 | 8% |
| Student > Postgraduate | 8 | 5% |
| Other | 25 | 16% |
| Unknown | 27 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 32 | 21% |
| Agricultural and Biological Sciences | 25 | 16% |
| Medicine and Dentistry | 25 | 16% |
| Biochemistry, Genetics and Molecular Biology | 10 | 7% |
| Engineering | 7 | 5% |
| Other | 19 | 12% |
| Unknown | 35 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2015.
All research outputs
#20,265,771
of 22,796,179 outputs
Outputs from Journal of Neuroinflammation
#2,304
of 2,627 outputs
Outputs of similar age
#295,776
of 353,053 outputs
Outputs of similar age from Journal of Neuroinflammation
#46
of 58 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,627 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,053 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.