You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
|
|---|---|
| Published in |
Journal of Neuroinflammation, March 2015
|
| DOI | 10.1186/s12974-015-0255-2 |
| Pubmed ID | |
| Authors |
Lalida Rojanathammanee, Angela M Floden, Gunjan D Manocha, Colin K Combs |
| Abstract |
Amyloid β (Aβ) peptide is hypothesized to stimulate microglia to acquire their characteristic proinflammatory phenotype in Alzheimer's disease (AD) brains. The specific mechanisms by which Aβ leads to microglial activation remain an area of interest for identifying attractive molecular targets for intervention. Based upon the fact that microglia express the proinflammatory transcription factor, nuclear factor of activated T cells (NFAT), we hypothesized that NFAT activity is required for the Aβ-stimulated microgliosis that occurs during disease. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Unknown | 70 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 27% |
| Student > Master | 13 | 18% |
| Researcher | 11 | 15% |
| Student > Bachelor | 5 | 7% |
| Other | 5 | 7% |
| Other | 5 | 7% |
| Unknown | 13 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 23 | 32% |
| Agricultural and Biological Sciences | 13 | 18% |
| Biochemistry, Genetics and Molecular Biology | 9 | 13% |
| Medicine and Dentistry | 4 | 6% |
| Chemistry | 2 | 3% |
| Other | 3 | 4% |
| Unknown | 17 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2022.
All research outputs
#2,293,542
of 23,437,201 outputs
Outputs from Journal of Neuroinflammation
#317
of 2,711 outputs
Outputs of similar age
#30,015
of 259,063 outputs
Outputs of similar age from Journal of Neuroinflammation
#1
of 44 outputs
Altmetric has tracked 23,437,201 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,711 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 259,063 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.