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Prevalence of pfhrp2 and pfhrp3 gene deletions in Puerto Lempira, Honduras

Overview of attention for article published in Malaria Journal, January 2015
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97 Mendeley
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Title
Prevalence of pfhrp2 and pfhrp3 gene deletions in Puerto Lempira, Honduras
Published in
Malaria Journal, January 2015
DOI 10.1186/s12936-014-0537-7
Pubmed ID
Authors

Joseph F Abdallah, Sheila Akinyi Okoth, Gustavo A Fontecha, Rosa Elena Mejia Torres, Engels I Banegas, María Luisa Matute, Sandra Tamara Mancero Bucheli, Ira F Goldman, Alexandre Macedo de Oliveira, John W Barnwell, Venkatachalam Udhayakumar

Abstract

Recent studies have demonstrated the deletion of the histidine-rich protein 2 (PfHRP2) gene (pfhrp2) in field isolates of Plasmodium falciparum, which could result in false negative test results when PfHRP2-based rapid diagnostic tests (RDTs) are used for malaria diagnosis. Although primary diagnosis of malaria in Honduras is determined based on microscopy, RDTs may be useful in remote areas. In this study, it was investigated whether there are deletions of the pfhrp2, pfhrp3 and their respective flanking genes in 68 P. falciparum parasite isolates collected from the city of Puerto Lempira, Honduras. In addition, further investigation considered the possible correlation between parasite population structure and the distribution of these gene deletions by genotyping seven neutral microsatellites.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 96 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 22%
Student > Ph. D. Student 16 16%
Researcher 15 15%
Student > Bachelor 6 6%
Other 4 4%
Other 12 12%
Unknown 23 24%
Readers by discipline Count As %
Medicine and Dentistry 22 23%
Biochemistry, Genetics and Molecular Biology 20 21%
Agricultural and Biological Sciences 10 10%
Immunology and Microbiology 7 7%
Nursing and Health Professions 2 2%
Other 11 11%
Unknown 25 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2015.
All research outputs
#18,403,994
of 22,796,179 outputs
Outputs from Malaria Journal
#5,037
of 5,562 outputs
Outputs of similar age
#255,946
of 351,798 outputs
Outputs of similar age from Malaria Journal
#86
of 116 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,562 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,798 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.