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Feeding a high-grain diet reduces the percentage of LPS clearance and enhances immune gene expression in goat liver

Overview of attention for article published in BMC Veterinary Research, March 2015
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Title
Feeding a high-grain diet reduces the percentage of LPS clearance and enhances immune gene expression in goat liver
Published in
BMC Veterinary Research, March 2015
DOI 10.1186/s12917-015-0376-y
Pubmed ID
Authors

Guangjun Chang, Kai Zhang, Tianle Xu, Di Jin, Hans-Martin Seyfert, Xiangzhen Shen, Su Zhuang

Abstract

The effects of feeding a high-grain (HG) diet on lipopolysaccharide (LPS) clearance and innate immune defence responses in the liver remain unclear. Therefore, we conducted the present study in which twelve female goats were randomly assigned to either a treatment group fed a HG diet (60% grain, n = 6) or a control group fed a low grain diet (LG; 40% grain, n = 6) for 6 weeks. Catheters were installed in the mesenteric, portal and hepatic veins, as well as one femoral artery of the goats, for determining blood flow and net clearance rate of LPS in the liver. Plasma and tissue samples were collected in the week 6 for analyzing pro-inflammatory cytokines, acute phase protein and biochemical parameters, as well as expression of genes involved in immune response.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 14%
Professor > Associate Professor 4 11%
Student > Bachelor 3 8%
Student > Doctoral Student 3 8%
Researcher 3 8%
Other 5 14%
Unknown 13 36%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 31%
Veterinary Science and Veterinary Medicine 3 8%
Biochemistry, Genetics and Molecular Biology 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Medicine and Dentistry 2 6%
Other 2 6%
Unknown 13 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2015.
All research outputs
#18,403,994
of 22,796,179 outputs
Outputs from BMC Veterinary Research
#1,924
of 3,050 outputs
Outputs of similar age
#209,139
of 286,004 outputs
Outputs of similar age from BMC Veterinary Research
#26
of 44 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,050 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,004 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.