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The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus

Overview of attention for article published in Clinical Epigenetics, March 2015
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3 X users
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1 Facebook page

Citations

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47 Mendeley
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Title
The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus
Published in
Clinical Epigenetics, March 2015
DOI 10.1186/s13148-015-0063-7
Pubmed ID
Authors

Shuangyan Luo, Yu Liu, Gongping Liang, Ming Zhao, Haijing Wu, Yunsheng Liang, Xiangning Qiu, Yixin Tan, Yong Dai, Susan Yung, Tak-Mao Chan, Qianjin Lu

Abstract

The pathogenesis of systemic lupus erythematosus (SLE) has not yet been completely elucidated. One of the hallmarks of SLE is the production of autoantibodies by uncontrolled over-activated B cells. Early B cell factor 1 (EBF1) contributes to the development, activation, and proliferation of B cells through activation of the AKT signaling pathway. Accumulating evidence has demonstrated that several microRNAs (miRNAs) contribute to the pathogenesis of autoimmune diseases through the regulation of B cells in SLE. We aim to investigate the expression patterns of miR-1246 in B cells and its contribution to pathogenesis of SLE.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 26%
Researcher 7 15%
Student > Postgraduate 4 9%
Student > Doctoral Student 4 9%
Student > Bachelor 3 6%
Other 9 19%
Unknown 8 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 30%
Medicine and Dentistry 8 17%
Biochemistry, Genetics and Molecular Biology 7 15%
Immunology and Microbiology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 2 4%
Unknown 11 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2015.
All research outputs
#14,806,069
of 22,796,179 outputs
Outputs from Clinical Epigenetics
#784
of 1,251 outputs
Outputs of similar age
#147,210
of 261,659 outputs
Outputs of similar age from Clinical Epigenetics
#35
of 41 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,251 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,659 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.