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Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

Overview of attention for article published in Molecular Cancer, September 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
1 X user
patent
1 patent
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
610 Dimensions

Readers on

mendeley
499 Mendeley
citeulike
1 CiteULike
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Title
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
Published in
Molecular Cancer, September 2011
DOI 10.1186/1476-4598-10-117
Pubmed ID
Authors

Mei Yang, Jingqi Chen, Fang Su, Bin Yu, Fengxi Su, Ling Lin, Yujie Liu, Jian-Dong Huang, Erwei Song

Abstract

Tumor-associated macrophages (TAMs) are alternatively activated cells induced by interleukin-4 (IL-4)-releasing CD4+ T cells. TAMs promote breast cancer invasion and metastasis; however, the mechanisms underlying these interactions between macrophages and tumor cells that lead to cancer metastasis remain elusive. Previous studies have found microRNAs (miRNAs) circulating in the peripheral blood and have identified microvesicles, or exosomes, as mediators of cell-cell communication. Therefore, one alternative mechanism for the promotion of breast cancer cell invasion by TAMs may be through macrophage-secreted exosomes, which would deliver invasion-potentiating miRNAs to breast cancer cells.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 499 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 1%
United Kingdom 4 <1%
Chile 2 <1%
Germany 2 <1%
Denmark 2 <1%
Brazil 2 <1%
Belgium 2 <1%
Switzerland 1 <1%
India 1 <1%
Other 10 2%
Unknown 468 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 133 27%
Researcher 107 21%
Student > Master 62 12%
Student > Bachelor 58 12%
Professor > Associate Professor 23 5%
Other 49 10%
Unknown 67 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 173 35%
Biochemistry, Genetics and Molecular Biology 95 19%
Medicine and Dentistry 71 14%
Immunology and Microbiology 17 3%
Engineering 16 3%
Other 47 9%
Unknown 80 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2022.
All research outputs
#4,567,247
of 23,006,268 outputs
Outputs from Molecular Cancer
#305
of 1,730 outputs
Outputs of similar age
#25,397
of 131,385 outputs
Outputs of similar age from Molecular Cancer
#3
of 15 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,730 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 131,385 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.