Title |
Role of SALL4 in the progression and metastasis of colorectal cancer.
|
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Published in |
Journal of Biomedical Science, January 2013
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DOI | 10.1186/1423-0127-20-6 |
Pubmed ID | |
Authors |
Mohammad Mahdi Forghanifard, Meysam Moghbeli, Reza Raeisossadati, Alireza Tavassoli, Afsaneh Javdani Mallak, Samaneh Boroumand-Noughabi, Mohammad Reza Abbaszadegan |
Abstract |
Human cancer cells resemble stem cells in expression signatures leading them to share some features, most notably, self-renewal. A complex network of transcription factors and signaling molecules are required for continuance of this trait. SALL4 is a zinc finger transcriptional activator crucial for maintenance of self-renewal in stem cells; however, its expression level has not yet been elucidated in colorectal tumor cells. To determine this level and probable clinicopathological consequences, its expression was analyzed. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Iran, Islamic Republic of | 1 | 4% |
France | 1 | 4% |
Unknown | 26 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 21% |
Student > Ph. D. Student | 4 | 14% |
Other | 3 | 11% |
Student > Postgraduate | 3 | 11% |
Student > Bachelor | 3 | 11% |
Other | 6 | 21% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 29% |
Medicine and Dentistry | 6 | 21% |
Agricultural and Biological Sciences | 5 | 18% |
Computer Science | 2 | 7% |
Physics and Astronomy | 1 | 4% |
Other | 2 | 7% |
Unknown | 4 | 14% |