Title |
Genome-wide analysis of alternative splicing in Chlamydomonas reinhardtii
|
---|---|
Published in |
BMC Genomics, February 2010
|
DOI | 10.1186/1471-2164-11-114 |
Pubmed ID | |
Authors |
Adam Labadorf, Alicia Link, Mark F Rogers, Julie Thomas, Anireddy SN Reddy, Asa Ben-Hur |
Abstract |
Genome-wide computational analysis of alternative splicing (AS) in several flowering plants has revealed that pre-mRNAs from about 30% of genes undergo AS. Chlamydomonas, a simple unicellular green alga, is part of the lineage that includes land plants. However, it diverged from land plants about one billion years ago. Hence, it serves as a good model system to study alternative splicing in early photosynthetic eukaryotes, to obtain insights into the evolution of this process in plants, and to compare splicing in simple unicellular photosynthetic and non-photosynthetic eukaryotes. We performed a global analysis of alternative splicing in Chlamydomonas reinhardtii using its recently completed genome sequence and all available ESTs and cDNAs. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
United Kingdom | 2 | 2% |
Germany | 1 | <1% |
Canada | 1 | <1% |
South Africa | 1 | <1% |
Spain | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 114 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 37 | 30% |
Researcher | 26 | 21% |
Student > Master | 15 | 12% |
Student > Bachelor | 12 | 10% |
Student > Doctoral Student | 6 | 5% |
Other | 18 | 15% |
Unknown | 10 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 82 | 66% |
Biochemistry, Genetics and Molecular Biology | 23 | 19% |
Computer Science | 4 | 3% |
Medicine and Dentistry | 1 | <1% |
Unknown | 14 | 11% |