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Combination of IFNα and poly-I:C reprograms bladder cancer microenvironment for enhanced CTL attraction

Overview of attention for article published in Journal for Immunotherapy of Cancer, March 2015
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Title
Combination of IFNα and poly-I:C reprograms bladder cancer microenvironment for enhanced CTL attraction
Published in
Journal for Immunotherapy of Cancer, March 2015
DOI 10.1186/s40425-015-0050-8
Pubmed ID
Authors

Ravikumar Muthuswamy, Liwen Wang, Jamie Pitteroff, Jeffrey R Gingrich, Pawel Kalinski

Abstract

BCG is a prototypal cancer immunotherapeutic factor currently approved of bladder cancer. In attempt to further enhance the effectiveness of immunotherapy of bladder cancer and, potentially, other malignancies, we evaluated the impact of BCG on local production of chemokines attracting the desirable effector CD8(+) T cells (CTLs) and undesirable myeloid-derived suppressor cell (MDSCs) and regulatory T(reg) cells, and the ability of bladder cancer tissues to attract CTLs.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Mexico 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Master 8 18%
Student > Bachelor 6 13%
Student > Ph. D. Student 6 13%
Other 4 9%
Other 7 16%
Unknown 5 11%
Readers by discipline Count As %
Medicine and Dentistry 12 27%
Biochemistry, Genetics and Molecular Biology 10 22%
Agricultural and Biological Sciences 10 22%
Immunology and Microbiology 6 13%
Nursing and Health Professions 1 2%
Other 0 0%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2020.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from Journal for Immunotherapy of Cancer
#3,105
of 3,421 outputs
Outputs of similar age
#207,110
of 278,396 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#11
of 12 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,396 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.