Title |
Emergence of Escherichia coli producing OXA-48 β-lactamase in the community in Switzerland
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Published in |
Antimicrobial Resistance & Infection Control, March 2015
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DOI | 10.1186/s13756-015-0051-x |
Pubmed ID | |
Authors |
Katrin Zurfluh, Magdalena T Nüesch-Inderbinen, Laurent Poirel, Patrice Nordmann, Herbert Hächler, Roger Stephan |
Abstract |
The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in the community in Switzerland. One thousand and eighty-six stool samples of healthy humans (staff members of a food-processing company which were screened for the occurrence of salmonellae) were collected in September 2014. After an initial enrichment-step, carbapenemase-producing Enterobacteriaceae were isolated from the carbapenem-containing selective medium SUPERCARBA II. Grown colonies from 11 samples were screened by PCR for the presence of bla KPC, bla NDM, bla OXA-48 and bla VIM. A single OXA-48-producing Escherichia coli was detected. Phylogenetic grouping and multi-locus sequence typing (MLST) revealed that this strain belonged to D:ST38, a type which had been previously reported in the UK, France, Lebanon and Egypt. The results of this study show that OXA-48-producing Enterobacteriaceae have started to spread into the community in Switzerland, and a continuous monitoring is necessary to better understand their dissemination in the human population as well as in animals and the environment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
United States | 1 | 1% |
Switzerland | 1 | 1% |
Unknown | 67 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 17% |
Researcher | 10 | 14% |
Student > Doctoral Student | 8 | 11% |
Student > Bachelor | 8 | 11% |
Student > Master | 7 | 10% |
Other | 14 | 20% |
Unknown | 11 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 15 | 21% |
Immunology and Microbiology | 11 | 16% |
Medicine and Dentistry | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Veterinary Science and Veterinary Medicine | 4 | 6% |
Other | 5 | 7% |
Unknown | 17 | 24% |