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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Enabling multiplexed testing of pooled donor cells through whole-genome sequencing
|
|---|---|
| Published in |
Genome Medicine, April 2018
|
| DOI | 10.1186/s13073-018-0541-6 |
| Pubmed ID | |
| Authors |
Yingleong Chan, Ying Kai Chan, Daniel B. Goodman, Xiaoge Guo, Alejandro Chavez, Elaine T. Lim, George M. Church |
| Abstract |
We describe a method that enables the multiplex screening of a pool of many different donor cell lines. Our method accurately predicts each donor proportion from the pool without requiring the use of unique DNA barcodes as markers of donor identity. Instead, we take advantage of common single nucleotide polymorphisms, whole-genome sequencing, and an algorithm to calculate the proportions from the sequencing data. By testing using simulated and real data, we showed that our method robustly predicts the individual proportions from a mixed-pool of numerous donors, thus enabling the multiplexed testing of diverse donor cells en masse.More information is available at https://pgpresearch.med.harvard.edu/poolseq/. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 22% |
| United Kingdom | 4 | 17% |
| Ecuador | 1 | 4% |
| Canada | 1 | 4% |
| Mexico | 1 | 4% |
| Spain | 1 | 4% |
| Unknown | 10 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 57% |
| Scientists | 10 | 43% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 26% |
| Researcher | 6 | 19% |
| Student > Master | 4 | 13% |
| Student > Doctoral Student | 3 | 10% |
| Other | 3 | 10% |
| Other | 2 | 6% |
| Unknown | 5 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 26% |
| Biochemistry, Genetics and Molecular Biology | 7 | 23% |
| Medicine and Dentistry | 3 | 10% |
| Immunology and Microbiology | 2 | 6% |
| Neuroscience | 2 | 6% |
| Other | 4 | 13% |
| Unknown | 5 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 75. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2020.
All research outputs
#578,301
of 25,727,480 outputs
Outputs from Genome Medicine
#106
of 1,609 outputs
Outputs of similar age
#12,971
of 342,319 outputs
Outputs of similar age from Genome Medicine
#1
of 24 outputs
Altmetric has tracked 25,727,480 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,609 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,319 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.