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Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral ischemia

Overview of attention for article published in Stem Cell Research & Therapy, September 2011
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1 X user

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Title
Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral ischemia
Published in
Stem Cell Research & Therapy, September 2011
DOI 10.1186/scrt79
Pubmed ID
Authors

Jung Yeon Lim, Chang Hyun Jeong, Jin Ae Jun, Seong Muk Kim, Chung Heon Ryu, Yun Hou, Wonil Oh, Jong Wook Chang, Sin-Soo Jeun

Abstract

Stem cell transplantation is a promising therapeutic strategy for the treatment of stroke. Mesenchymal stem cells (MSCs) are a potential cell source for clinical application because they can be easily obtained and cultivated with a high proliferative capacity. The safety and efficacy of cell therapy depends on the mode of cell administration. To determine the therapeutic potential of intrathecal administration of MSCs by lumbar puncture (LP), we administrated human umbilical cord blood-derived MSCs (hUCB-MSCs) intrathecally into the lumbar spinal cord or intravenously into the tail vein in a rat model of stroke, and then investigated whether hUCB-MSCs could enter the brain, survive, and improve post-stroke neurological functional recovery.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 1%
United Kingdom 1 1%
Korea, Republic of 1 1%
Unknown 85 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 16%
Student > Bachelor 14 16%
Student > Ph. D. Student 13 15%
Student > Master 13 15%
Other 5 6%
Other 17 19%
Unknown 12 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 28%
Medicine and Dentistry 24 27%
Engineering 6 7%
Biochemistry, Genetics and Molecular Biology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 10 11%
Unknown 16 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2011.
All research outputs
#18,297,449
of 22,653,392 outputs
Outputs from Stem Cell Research & Therapy
#1,719
of 2,410 outputs
Outputs of similar age
#108,688
of 130,581 outputs
Outputs of similar age from Stem Cell Research & Therapy
#5
of 5 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,410 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 130,581 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.