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Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo

Overview of attention for article published in BMC Biology, January 2011
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1 tweeter
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Citations

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85 Mendeley
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Title
Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo
Published in
BMC Biology, January 2011
DOI 10.1186/1741-7007-9-65
Pubmed ID
Authors

Federica Parisi, Sara Riccardo, Margaret Daniel, Mahesh Saqcena, Nandini Kundu, Annalisa Pession, Daniela Grifoni, Hugo Stocker, Esteban Tabak, Paola Bellosta

Abstract

Genetic studies in Drosophila melanogaster reveal an important role for Myc in controlling growth. Similar studies have also shown how components of the insulin and target of rapamycin (TOR) pathways are key regulators of growth. Despite a few suggestions that Myc transcriptional activity lies downstream of these pathways, a molecular mechanism linking these signaling pathways to Myc has not been clearly described. Using biochemical and genetic approaches we tried to identify novel mechanisms that control Myc activity upon activation of insulin and TOR signaling pathways.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
India 1 1%
Sweden 1 1%
Spain 1 1%
Germany 1 1%
Unknown 79 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 44%
Researcher 16 19%
Student > Master 12 14%
Student > Doctoral Student 6 7%
Student > Bachelor 3 4%
Other 6 7%
Unknown 5 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 56%
Biochemistry, Genetics and Molecular Biology 25 29%
Neuroscience 4 5%
Medicine and Dentistry 2 2%
Unknown 6 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2012.
All research outputs
#7,571,124
of 12,554,200 outputs
Outputs from BMC Biology
#935
of 1,132 outputs
Outputs of similar age
#55,916
of 95,147 outputs
Outputs of similar age from BMC Biology
#3
of 3 outputs
Altmetric has tracked 12,554,200 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.7. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,147 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.