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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Detecting non-allelic homologous recombination from high-throughput sequencing data
|
|---|---|
| Published in |
Genome Biology, April 2015
|
| DOI | 10.1186/s13059-015-0633-1 |
| Pubmed ID | |
| Authors |
Matthew M Parks, Charles E Lawrence, Benjamin J Raphael |
| Abstract |
Non-allelic homologous recombination (NAHR) is a common mechanism for generating genome rearrangements and is implicated in numerous genetic disorders, but its detection in high-throughput sequencing data poses a serious challenge. We present a probabilistic model of NAHR and demonstrate its ability to find NAHR in low coverage sequencing data from 44 individuals. We identify NAHR-mediated deletions or duplications in 109 of 324 potential NAHR loci in at least one of the individuals. These calls segregate by ancestry, are more common in closely spaced repeats, often result in duplicated genes or pseudogenes, and affect highly studied genes such as GBA and CYP2E1. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 44% |
| United Kingdom | 3 | 19% |
| Germany | 1 | 6% |
| India | 1 | 6% |
| Unknown | 4 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 11 | 69% |
| Members of the public | 4 | 25% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| France | 1 | <1% |
| Unknown | 109 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 22% |
| Student > Bachelor | 21 | 19% |
| Researcher | 10 | 9% |
| Student > Doctoral Student | 9 | 8% |
| Student > Master | 9 | 8% |
| Other | 16 | 14% |
| Unknown | 22 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 36% |
| Agricultural and Biological Sciences | 27 | 24% |
| Computer Science | 9 | 8% |
| Medicine and Dentistry | 8 | 7% |
| Mathematics | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 24 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#2,450,102
of 25,373,627 outputs
Outputs from Genome Biology
#1,992
of 4,467 outputs
Outputs of similar age
#30,903
of 279,935 outputs
Outputs of similar age from Genome Biology
#37
of 66 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,935 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.