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Psychiatric disorders, psychotropic medication use and falls among women: an observational study

Overview of attention for article published in BMC Psychiatry, April 2015
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Title
Psychiatric disorders, psychotropic medication use and falls among women: an observational study
Published in
BMC Psychiatry, April 2015
DOI 10.1186/s12888-015-0439-4
Pubmed ID
Authors

Lana J Williams, Julie A Pasco, Amanda L Stuart, Felice N Jacka, Sharon L Brennan, Amelia G Dobbins, Risto Honkanen, Heli Koivumaa-Honkanen, Päivi H Rauma, Michael Berk

Abstract

Psychotropic agents known to cause sedation are associated with an increased risk of falls, but the role of psychiatric illness as an independent risk factor for falls is not clear. Thus, this study aimed to investigate the association between psychiatric disorders, psychotropic medication use and falls risk. This study examined data collected from 1062 women aged 20-93 yr (median 50 yr) participating in the Geelong Osteoporosis Study, a large, ongoing, population-based study. Depressive and anxiety disorders for the preceding 12-month period were ascertained by clinical interview. Current medication use and falls history were self-reported. Participants were classified as fallers if they had fallen to the ground at least twice during the same 12-month period. Anthropometry, demographic, medical and lifestyle factors were determined. Logistic regression was used to test the associations, after adjusting for potential confounders. Fifty-six women (5.3%) were classified as fallers. Those meeting criteria for depression within the past 12 months had a 2.4-fold increased odds of falling (unadjusted OR = 2.4, 95% CI 1.2-4.5). Adjustment for age and mobility strengthened the relationship (adjusted OR = 2.7, 95% CI 1.4-5.2) between depression and falling, with results remaining unchanged following further adjustment for psychotropic medication use (adjusted OR = 2.7, 95% CI 1.3-5.6). In contrast, past (prior to 12-month) depression were not associated with falls. No association was observed between anxiety and falls risk. Falling was associated with psychotropic medication use (unadjusted OR = 2.8, 95% CI 1.5-5.2), as well as antidepressant (unadjusted OR = 2.4, 95% CI 1.2-4.8) and benzodiazepine use (unadjusted OR = 3.4, 95% CI 1.6-7.3); associations remained unchanged following adjustment for potential confounders. The likelihood of falls was increased among those with depression within the past 12 months, independent of psychotropic medication use and other recognised confounders, suggesting an independent effect of depression on falls risk. Psychotropic drug use was also confirmed as an independent risk factor for falls, but anxiety disorders were not. Further research into the underlying mechanisms is warranted.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
United States 1 1%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 19%
Student > Bachelor 12 14%
Student > Ph. D. Student 10 12%
Professor 6 7%
Researcher 5 6%
Other 19 22%
Unknown 17 20%
Readers by discipline Count As %
Medicine and Dentistry 27 32%
Nursing and Health Professions 11 13%
Pharmacology, Toxicology and Pharmaceutical Science 8 9%
Psychology 5 6%
Engineering 4 5%
Other 9 11%
Unknown 21 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2018.
All research outputs
#14,807,732
of 22,799,071 outputs
Outputs from BMC Psychiatry
#3,190
of 4,683 outputs
Outputs of similar age
#148,936
of 264,940 outputs
Outputs of similar age from BMC Psychiatry
#56
of 89 outputs
Altmetric has tracked 22,799,071 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,683 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,940 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.