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Effect of Moringa oleifera consumption on diabetic rats

Overview of attention for article published in BMC Complementary Medicine and Therapies, April 2018
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Title
Effect of Moringa oleifera consumption on diabetic rats
Published in
BMC Complementary Medicine and Therapies, April 2018
DOI 10.1186/s12906-018-2180-2
Pubmed ID
Authors

A. Villarruel-López, D. A. López-de la Mora, O. D. Vázquez-Paulino, A. G. Puebla-Mora, Ma R. Torres-Vitela, L. A. Guerrero-Quiroz, K. Nuño

Abstract

Therapeutic use of leaves of M. oleifera has been evaluated in diabetes because of its possible capacity to decrease blood glucose and lipids concentration after ingestion, as result of the polyphenols content and others compounds. Nevertheless most results have been obtain from leaf extract, therefore this study would use leaf powder as the regular way of consumption of population to know effects over toxicity glucose, triglycerides, cholesterol, corporal weight, and predominant groups of microbiota. Powdered leaf was administrated in different doses to know toxicity and genotoxicity using LD50 and micronuclei assay. Hyperglycemia was induced by alloxan on Sprague Dawley rats. Glucose and body weight were measured once a week meanwhile cholesterol and triglycerides were analyzed at the end of the study by commercial kits. Different organs were examined by hematoxylin-eosin technique. Lactic acid bacteria and Enterobacteriaceae were enumerated from stool samples. The tested doses revealed no lethal dose and no significant differences in genotoxicity parameter. The consumption of the leaves showed a hypoglycemic effect (< 250 mg/dL in diabetic M. oleifera treated group), however in corporal weight showed an increased (> 30 g over no M. oleifera treated groups). There was no change in enumeration of lactic acid bacteria (8.4 CFU/g) but there were differences in the predominance of type of lactobacillus and enterobacteria enumeration. These results help to increase information over the most popular use of M. oleifera and its safety. However there are needed more studies over the hypoglycemic mechanisms and effects over intestinal microbiota.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 343 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 343 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 50 15%
Student > Master 31 9%
Researcher 21 6%
Student > Ph. D. Student 19 6%
Lecturer 17 5%
Other 39 11%
Unknown 166 48%
Readers by discipline Count As %
Medicine and Dentistry 45 13%
Biochemistry, Genetics and Molecular Biology 28 8%
Agricultural and Biological Sciences 27 8%
Pharmacology, Toxicology and Pharmaceutical Science 22 6%
Nursing and Health Professions 16 5%
Other 32 9%
Unknown 173 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2018.
All research outputs
#19,594,120
of 24,093,053 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,567
of 3,782 outputs
Outputs of similar age
#259,452
of 332,929 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#49
of 85 outputs
Altmetric has tracked 24,093,053 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,782 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,929 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.