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Venomous snake bites: clinical diagnosis and treatment

Overview of attention for article published in Journal of Intensive Care, April 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

8 X users
1 Facebook page
1 Wikipedia page
1 YouTube creator


87 Dimensions

Readers on

252 Mendeley
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Venomous snake bites: clinical diagnosis and treatment
Published in
Journal of Intensive Care, April 2015
DOI 10.1186/s40560-015-0081-8
Pubmed ID

Toru Hifumi, Atsushi Sakai, Yutaka Kondo, Akihiko Yamamoto, Nobuya Morine, Manabu Ato, Keigo Shibayama, Kazuo Umezawa, Nobuaki Kiriu, Hiroshi Kato, Yuichi Koido, Junichi Inoue, Kenya Kawakita, Yasuhiro Kuroda


Snake bites are life-threatening injuries that can require intensive care. The diagnosis and treatment of venomous snake bites is sometimes difficult for clinicians because sufficient information has not been provided in clinical practice. Here we review the literature to present the proper management of bites by mamushi, habu, and yamakagashi snakes, which widely inhabit Japan and other Asian countries. No definite diagnostic markers or kits are available for clinical practice; therefore, definitive diagnosis of snake-venom poisoning requires positive identification of the snake and observation of the clinical manifestations of envenomation. Mamushi (Gloydius blomhoffii) bites cause swelling and pain that spreads gradually from the bite site. The platelet count gradually decreases due to the platelet aggregation activity of the venom and can decrease to <100,000/mm(3). If the venom gets directly injected into the blood vessel, the platelet count rapidly decreases to <10,000/mm(3) within 1 h after the bite. Habu (Protobothrops flavoviridis) bites result in swelling within 30 min. Severe cases manifest not only local signs but also general symptoms such as vomiting, cyanosis, loss of consciousness, and hypotension. Yamakagashi (Rhabdophis tigrinus) bites induce life-threatening hemorrhagic symptoms and severe disseminated intravascular coagulation with a fibrinolytic phenotype, resulting in hypofibrinogenemia and increased levels of fibrinogen degradation products. Previously recommended first-aid measures such as tourniquets, incision, and suction are strongly discouraged. Once airway, breathing, and circulation have been established, a rapid, detailed history should be obtained. If a snake bite is suspected, hospital admission should be considered for further follow-up. All venomous snake bites can be effectively treated with antivenom. Side effects of antivenom should be prevented by sufficient preparation. Approved antivenoms for mamushi and habu are available. Yamakagashi antivenom is used as an off-label drug in Japan, requiring clinicians to join a clinical research group for its use in clinical practice.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 252 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
Spain 1 <1%
Colombia 1 <1%
Brazil 1 <1%
Unknown 248 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 34 13%
Student > Master 33 13%
Student > Postgraduate 31 12%
Researcher 23 9%
Other 18 7%
Other 49 19%
Unknown 64 25%
Readers by discipline Count As %
Medicine and Dentistry 80 32%
Agricultural and Biological Sciences 24 10%
Biochemistry, Genetics and Molecular Biology 22 9%
Nursing and Health Professions 20 8%
Pharmacology, Toxicology and Pharmaceutical Science 12 5%
Other 25 10%
Unknown 69 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2022.
All research outputs
of 26,213,251 outputs
Outputs from Journal of Intensive Care
of 592 outputs
Outputs of similar age
of 279,673 outputs
Outputs of similar age from Journal of Intensive Care
of 10 outputs
Altmetric has tracked 26,213,251 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 592 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,673 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.