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Signaling by exosomal microRNAs in cancer

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, April 2015
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Mentioned by

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1 tweeter

Citations

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113 Dimensions

Readers on

mendeley
148 Mendeley

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Title
Signaling by exosomal microRNAs in cancer
Published in
Journal of Experimental & Clinical Cancer Research, April 2015
DOI 10.1186/s13046-015-0148-3
Pubmed ID
25886763
Authors

Germana Falcone, Armando Felsani, Igea D’Agnano

Abstract

A class of small non-coding RNAs, the microRNAs (miRNAs), have recently attracted great attention in cancer research since they play a central role in regulation of gene-expression and miRNA aberrant expression is found in almost all types of human cancer. The discovery of circulating miRNAs in body fluids and the finding that they are often tumor specific and can be detected early in tumorigenesis has soon led to the evaluation of their possible use as cancer biomarkers and treatment-response predictors. The evidence that tumor cells communicate via the secretion and delivery of miRNAs packed into tumor-released microvesicles has prompted to investigate miRNA contribution as signaling molecules to the establishment and maintenance of the tumor microenvironment and the metastatic niche in cancer. In this review we highlight the recent advances on the role of exosomal miRNAs as mediators of cancer cell-to-cell communication.

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Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 2 1%
Finland 1 <1%
United States 1 <1%
Belgium 1 <1%
Unknown 143 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 22%
Researcher 25 17%
Student > Master 19 13%
Student > Bachelor 15 10%
Student > Doctoral Student 11 7%
Other 25 17%
Unknown 21 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 39 26%
Agricultural and Biological Sciences 33 22%
Medicine and Dentistry 29 20%
Pharmacology, Toxicology and Pharmaceutical Science 7 5%
Immunology and Microbiology 4 3%
Other 11 7%
Unknown 25 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2015.
All research outputs
#14,703,374
of 16,669,654 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#971
of 1,354 outputs
Outputs of similar age
#191,167
of 231,826 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#1
of 1 outputs
Altmetric has tracked 16,669,654 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,354 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,826 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them

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