Title |
The Cryptosporidium parvum Kinome
|
---|---|
Published in |
BMC Genomics, September 2011
|
DOI | 10.1186/1471-2164-12-478 |
Pubmed ID | |
Authors |
Jennifer D Artz, Amy K Wernimont, Abdellah Allali-Hassani, Yong Zhao, Mehrnaz Amani, Yu-Hui Lin, Guillermo Senisterra, Gregory A Wasney, Oleg Fedorov, Oliver King, Annette Roos, Vlad V Lunin, Wei Qiu, Patrick Finerty, Ashley Hutchinson, Irene Chau, Frank von Delft, Farrell MacKenzie, Jocelyne Lew, Ivona Kozieradzki, Masoud Vedadi, Matthieu Schapira, Chao Zhang, Kevan Shokat, Tom Heightman, Raymond Hui |
Abstract |
Hundreds of millions of people are infected with cryptosporidiosis annually, with immunocompromised individuals suffering debilitating symptoms and children in socioeconomically challenged regions at risk of repeated infections. There is currently no effective drug available. In order to facilitate the pursuit of anti-cryptosporidiosis targets and compounds, our study spans the classification of the Cryptosporidium parvum kinome and the structural and biochemical characterization of representatives from the CDPK family and a MAP kinase. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Finland | 1 | 1% |
United States | 1 | 1% |
Unknown | 71 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 25% |
Researcher | 11 | 15% |
Student > Bachelor | 7 | 10% |
Professor > Associate Professor | 6 | 8% |
Other | 6 | 8% |
Other | 11 | 15% |
Unknown | 14 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 25 | 34% |
Biochemistry, Genetics and Molecular Biology | 13 | 18% |
Medicine and Dentistry | 9 | 12% |
Immunology and Microbiology | 3 | 4% |
Computer Science | 3 | 4% |
Other | 3 | 4% |
Unknown | 17 | 23% |