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Community acquired multi-drug resistant clinical isolates of Escherichia coli in a tertiary care center of Nepal

Overview of attention for article published in Antimicrobial Resistance and Infection Control, May 2015
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  • Good Attention Score compared to outputs of the same age (70th percentile)

Mentioned by

twitter
8 tweeters

Citations

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38 Dimensions

Readers on

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60 Mendeley
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Title
Community acquired multi-drug resistant clinical isolates of Escherichia coli in a tertiary care center of Nepal
Published in
Antimicrobial Resistance and Infection Control, May 2015
DOI 10.1186/s13756-015-0059-2
Pubmed ID
Authors

Shamshul Ansari, Hari Prasad Nepal, Rajendra Gautam, Sony Shrestha, Puja Neopane, Ganga Gurung, Moti Lal Chapagain

Abstract

Multi-drug resistance (MDR) in Gram-negative organisms is an alarming problem in the world. MDR and extensively-drug resistance (XDR) is in increasing trend due to the production of different types of beta (β)-lactamases. Thus the aim of this study was to document the incidence of MDR and XDR in clinical isolates of Escherichia coli and also to find out the enzymatic mechanisms of β-lactam antibiotics resistance. Two hundred clinical isolates of Escherichia coli (E. coli) identified by standard laboratory methods were studied. Antibiotic susceptibility profile was performed for all the isolates and the suspected isolates were phenotypically tested for the production of extended spectrum β-lactamase (ESBL), metallo β-lactamase (MBL) and AmpC β-lactamase (AmpC) by recommended methods. Around three-fourth (78%) of the total isolates were multi-drug resistant. ESBL, MBL and AmpC production was found in 24%, 15% and 9% of isolates respectively. Amikacin, chloramphenicol and colistin were found to be the most effective antibiotics. High percentage of MDR was observed. β-lactamase mediated resistance was also high. Thus, regular surveillance of drug resistance due to β-lactamases production and infection control policy are of utmost importance to minimize the spread of resistant strains.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 23%
Student > Bachelor 11 18%
Student > Ph. D. Student 11 18%
Researcher 10 17%
Student > Postgraduate 4 7%
Other 5 8%
Unknown 5 8%
Readers by discipline Count As %
Medicine and Dentistry 12 20%
Agricultural and Biological Sciences 12 20%
Immunology and Microbiology 10 17%
Pharmacology, Toxicology and Pharmaceutical Science 6 10%
Biochemistry, Genetics and Molecular Biology 5 8%
Other 8 13%
Unknown 7 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2015.
All research outputs
#4,119,356
of 14,460,564 outputs
Outputs from Antimicrobial Resistance and Infection Control
#455
of 789 outputs
Outputs of similar age
#65,475
of 228,936 outputs
Outputs of similar age from Antimicrobial Resistance and Infection Control
#1
of 1 outputs
Altmetric has tracked 14,460,564 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 789 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,936 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them