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Neoadjuvant intraperitoneal chemotherapy followed by radical surgery and HIPEC in patients with very advanced gastric cancer and peritoneal metastases: report of an initial experience in a western…

Overview of attention for article published in World Journal of Surgical Oncology, March 2018
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Title
Neoadjuvant intraperitoneal chemotherapy followed by radical surgery and HIPEC in patients with very advanced gastric cancer and peritoneal metastases: report of an initial experience in a western single center
Published in
World Journal of Surgical Oncology, March 2018
DOI 10.1186/s12957-018-1363-0
Pubmed ID
Authors

Bianca Escorel Costa Fava, Wilson Luiz da Costa, Maria Luiza L. Medeiros, Marina Sonagli, Héber Salvador de Castro Ribeiro, Alessandro L. Diniz, André L. Godoy, Igor C. de Farias, Victor Hugo Fonseca de Jesus, Maria Dirlei F. S. Begnami, Felipe J. F. Coimbra

Abstract

The association of preoperative systemic and intraperitoneal chemotherapy has been described in Eastern patients with very good outcomes in treatment responders. The aim of this paper is to describe the initial results of this multidisciplinary regimen in gastric cancer patients with very advanced peritoneal metastases. We present here the first four cases who received the treatment protocol. They had a baseline PCI between 19 and 33. Two patients had received systemic chemotherapy prior to this regimen. Three of them had significant response and were taken to cytoreductive surgery, while one patient who had 12 cycles of chemotherapy previously showed signs of disease progression and subsequently died. There was no significant postoperative morbidity, and three patients remain alive, two of them with no signs of recurrence. Systemic and intraperitoneal chemotherapy led to a marked response in peritoneal disease extent in our initial experience and allowed three of four patients with very advanced disease to be treated with cytoreductive surgery.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Student > Master 5 19%
Other 3 11%
Student > Bachelor 3 11%
Student > Ph. D. Student 2 7%
Other 6 22%
Unknown 3 11%
Readers by discipline Count As %
Medicine and Dentistry 16 59%
Biochemistry, Genetics and Molecular Biology 2 7%
Nursing and Health Professions 2 7%
Materials Science 2 7%
Sports and Recreations 1 4%
Other 1 4%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2020.
All research outputs
#15,748,537
of 25,712,965 outputs
Outputs from World Journal of Surgical Oncology
#467
of 2,159 outputs
Outputs of similar age
#192,036
of 348,503 outputs
Outputs of similar age from World Journal of Surgical Oncology
#13
of 29 outputs
Altmetric has tracked 25,712,965 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,159 research outputs from this source. They receive a mean Attention Score of 2.2. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,503 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.