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Extracting research-quality phenotypes from electronic health records to support precision medicine

Overview of attention for article published in Genome Medicine, April 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

twitter
26 X users
facebook
3 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
192 Dimensions

Readers on

mendeley
307 Mendeley
citeulike
3 CiteULike
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Title
Extracting research-quality phenotypes from electronic health records to support precision medicine
Published in
Genome Medicine, April 2015
DOI 10.1186/s13073-015-0166-y
Pubmed ID
Authors

Wei-Qi Wei, Joshua C Denny

Abstract

The convergence of two rapidly developing technologies - high-throughput genotyping and electronic health records (EHRs) - gives scientists an unprecedented opportunity to utilize routine healthcare data to accelerate genomic discovery. Institutions and healthcare systems have been building EHR-linked DNA biobanks to enable such a vision. However, the precise extraction of detailed disease and drug-response phenotype information hidden in EHRs is not an easy task. EHR-based studies have successfully replicated known associations, made new discoveries for diseases and drug response traits, rapidly contributed cases and controls to large meta-analyses, and demonstrated the potential of EHRs for broad-based phenome-wide association studies. In this review, we summarize the advantages and challenges of repurposing EHR data for genetic research. We also highlight recent notable studies and novel approaches to provide an overview of advanced EHR-based phenotyping.

X Demographics

X Demographics

The data shown below were collected from the profiles of 26 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 307 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 2%
Netherlands 1 <1%
Australia 1 <1%
Unknown 300 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 68 22%
Student > Ph. D. Student 67 22%
Student > Master 37 12%
Other 24 8%
Student > Bachelor 19 6%
Other 42 14%
Unknown 50 16%
Readers by discipline Count As %
Computer Science 66 21%
Medicine and Dentistry 60 20%
Biochemistry, Genetics and Molecular Biology 34 11%
Agricultural and Biological Sciences 19 6%
Social Sciences 9 3%
Other 52 17%
Unknown 67 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2017.
All research outputs
#2,071,426
of 25,390,970 outputs
Outputs from Genome Medicine
#462
of 1,584 outputs
Outputs of similar age
#25,893
of 278,125 outputs
Outputs of similar age from Genome Medicine
#13
of 28 outputs
Altmetric has tracked 25,390,970 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,584 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,125 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.