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Strategies to uncover undiagnosed HIV infection among heterosexuals at high risk and link them to HIV care with high retention: a “seek, test, treat, and retain” study

Overview of attention for article published in BMC Public Health, May 2015
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Title
Strategies to uncover undiagnosed HIV infection among heterosexuals at high risk and link them to HIV care with high retention: a “seek, test, treat, and retain” study
Published in
BMC Public Health, May 2015
DOI 10.1186/s12889-015-1816-0
Pubmed ID
Authors

Marya Gwadz, Charles M. Cleland, Holly Hagan, Samuel Jenness, Alexandra Kutnick, Noelle R. Leonard, Elizabeth Applegate, Amanda S. Ritchie, Angela Banfield, Mindy Belkin, Bridget Cross, Montserrat Del Olmo, Katharine Ha, Belkis Y. Martinez, Talaya McCright-Gill, Quentin L. Swain, David C. Perlman, Ann E. Kurth, the BCAP Collaborative Research Team

Abstract

Over 50,000 individuals become infected with HIV annually in the U.S, and over a quarter of HIV infected individuals are heterosexuals. Undiagnosed HIV infection, as well as a lack of retention in care among those diagnosed, are both primary factors contributing to ongoing HIV incidence. Further, there are racial/ethnic disparities in undiagnosed HIV and engagement in care, with African Americans/Blacks and Latinos remaining undiagnosed longer and less engaged in care than Whites, signaling the need for culturally targeted intervention approaches to seek and test those with undiagnosed HIV infection, and link them to care with high retention. The study has two components: one to seek out and test heterosexuals at high risk for HIV infection, and another to link those found infected to HIV care with high retention. We will recruit sexually active African American/Black and Latino adults who have opposite sex partners, negative or unknown HIV status, and reside in locations with high poverty and HIV prevalence. The "Seek and Test" component will compare the efficacy and cost effectiveness of two strategies to uncover undiagnosed HIV infection: venue-based sampling and respondent-driven sampling (RDS). Among those recruited by RDS and found to have HIV infection, a "Treat and Retain" component will assess the efficacy of a peer-driven intervention compared to a control arm with respect to time to an HIV care appointment and health indicators using a cluster randomized controlled trial design to minimize contamination. RDS initial seeds will be randomly assigned to the intervention or control arm at a 1:1 ratio and all recruits will be assigned to the same arm as the recruiter. Participants will be followed for 12 months with outcomes assessed using medical records and biomarkers, such as HIV viral load. Heterosexuals do not test for HIV as frequently as and are diagnosed later than other risk groups. The study has the potential to contribute an efficient, innovative, and sustainable multi-level recruitment approach and intervention to the HIV prevention portfolio. Because the majority of heterosexuals at high risk are African American/Black or Latino, the study has great potential to reduce racial/ethnic disparities in HIV/AIDS. ClinicalTrials.gov, NCT01607541 , Registered May 23, 2012.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 1%
United States 1 1%
Brazil 1 1%
Unknown 90 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 19%
Student > Master 17 18%
Student > Ph. D. Student 14 15%
Student > Bachelor 6 6%
Student > Doctoral Student 4 4%
Other 14 15%
Unknown 20 22%
Readers by discipline Count As %
Medicine and Dentistry 20 22%
Nursing and Health Professions 15 16%
Social Sciences 7 8%
Agricultural and Biological Sciences 5 5%
Psychology 5 5%
Other 14 15%
Unknown 27 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2015.
All research outputs
#18,409,030
of 22,803,211 outputs
Outputs from BMC Public Health
#12,845
of 14,856 outputs
Outputs of similar age
#191,901
of 263,961 outputs
Outputs of similar age from BMC Public Health
#202
of 234 outputs
Altmetric has tracked 22,803,211 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,856 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,961 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 234 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.