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Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis

Overview of attention for article published in Reproductive Biology and Endocrinology, June 2011
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Title
Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis
Published in
Reproductive Biology and Endocrinology, June 2011
DOI 10.1186/1477-7827-9-92
Pubmed ID
Authors

Yagmur Muftuoglu, Gabriela Mustata

Abstract

The present study compares antiepileptic drugs and aromatase (CYP19) inhibitors for chemical and structural similarity. Human aromatase is well known as an important pharmacological target in anti-breast cancer therapy, but recent research demonstrates its role in epileptic seizures, as well. The current antiepileptic treatment methods cause severe side effects that endanger patient health and often preclude continued use. As a result, less toxic and more tolerable antiepileptic drugs (AEDs) are needed, especially since every individual responds differently to given treatment options.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 5%
Luxembourg 1 5%
Unknown 18 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 30%
Researcher 3 15%
Student > Doctoral Student 3 15%
Other 2 10%
Student > Master 1 5%
Other 1 5%
Unknown 4 20%
Readers by discipline Count As %
Psychology 4 20%
Agricultural and Biological Sciences 3 15%
Computer Science 2 10%
Biochemistry, Genetics and Molecular Biology 2 10%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 7 35%