↓ Skip to main content

Central venous-to-arterial carbon dioxide difference as a prognostic tool in high-risk surgical patients

Overview of attention for article published in Critical Care, December 2015
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

Mentioned by

twitter
20 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
57 Dimensions

Readers on

mendeley
105 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Central venous-to-arterial carbon dioxide difference as a prognostic tool in high-risk surgical patients
Published in
Critical Care, December 2015
DOI 10.1186/s13054-015-0917-6
Pubmed ID
Authors

Emmanuel Robin, Emmanuel Futier, Oscar Pires, Maher Fleyfel, Benoit Tavernier, Gilles Lebuffe, Benoit Vallet

Abstract

The purpose of this study was to evaluate the clinical relevance of high values of central venous-to-arterial carbon dioxide difference (PCO2 gap) in high risk surgical patients admitted in postoperative intensive care unit (ICU). We hypothesized that PCO2 gap could serve as a useful tool to identify patients still requiring hemodynamic optimization at ICU admission. 115 patients were included in this prospective single centre observational study during a one year period. High risk surgical inclusion criteria were adapted from Schoemaker et al. Demographic and biological data, PCO2 gap, ScvO2, lactate level and postoperative complications were recorded for all patients at ICU admission, 6 hours and 12 hours after admission. A total of 78 (68%) patients developed postoperative complications whom 54 (47%) developed organ failure. From H0 to H12, there was a significant difference for mean PCO2 gap (8.7 ± 2.8 mmHg vs 5.1 ± 2.6 mmHg; p = 0.001) and median lactate values (1.54[1.1-3.2] mmol.l(-1) vs 1.06 ± [0.8-1.8] mmol.l(-1); p = 0.003) between patients who developed postoperative complications and those who did not. These differences were maximal at admission in ICU. At ICU admission, area under the receiver operating characteristic curve for occurrence of postoperative complications was 0.86 for the PCO2 gap compared to SOFA score (0.82), SAPS II score (0.67), lactate level (0.67). Threshold value for PCO2 gap was 5.8 mmHg. Multivariate analysis showed that only high PCO2 gap and a high SOFA score were independently associated with the occurrence of postoperative complications. A high PCO2 gap (≥6 mmHg) was associated to more organ failure, an increase in duration of mechanical ventilation and length of hospital stay. A high PCO2 gap at admission in postoperative ICU was significantly associated with increased postoperative complications in high risk surgical patients. If the increase in PCO2 gap is secondary to tissue hypoperfusion then the PCO2 gap might be a useful tool complementary to ScvO2 as therapeutic target.

X Demographics

X Demographics

The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Czechia 1 <1%
Egypt 1 <1%
Mexico 1 <1%
Denmark 1 <1%
United States 1 <1%
Unknown 99 94%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 14 13%
Student > Master 14 13%
Other 12 11%
Student > Ph. D. Student 9 9%
Student > Doctoral Student 8 8%
Other 24 23%
Unknown 24 23%
Readers by discipline Count As %
Medicine and Dentistry 66 63%
Neuroscience 3 3%
Biochemistry, Genetics and Molecular Biology 2 2%
Engineering 2 2%
Sports and Recreations 1 <1%
Other 3 3%
Unknown 28 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2016.
All research outputs
#2,755,292
of 25,373,627 outputs
Outputs from Critical Care
#2,384
of 6,554 outputs
Outputs of similar age
#44,077
of 395,397 outputs
Outputs of similar age from Critical Care
#191
of 466 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,397 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 466 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.