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Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

Overview of attention for article published in BMC Systems Biology, October 2011
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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2 X users

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140 Mendeley
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Title
Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data
Published in
BMC Systems Biology, October 2011
DOI 10.1186/1752-0509-5-162
Pubmed ID
Authors

Seda Genc, Isil A Kurnaz, Mustafa Ozilgen

Abstract

Neuro-glial interactions are important for normal functioning of the brain as well as brain energy metabolism. There are two major working models--in the classical view, both neurons and astrocytes can utilize glucose as the energy source through oxidative metabolism, whereas in the astrocyte-neuron lactate shuttle hypothesis (ANLSH) it is the astrocyte which can consume glucose through anaerobic glycolysis to pyruvate and then to lactate, and this lactate is secreted to the extracellular space to be taken up by the neuron for further oxidative degradation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 140 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Chile 1 <1%
United States 1 <1%
Ireland 1 <1%
Unknown 136 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 23%
Researcher 24 17%
Student > Master 23 16%
Student > Bachelor 20 14%
Student > Doctoral Student 6 4%
Other 20 14%
Unknown 15 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 25%
Neuroscience 30 21%
Medicine and Dentistry 20 14%
Biochemistry, Genetics and Molecular Biology 18 13%
Engineering 5 4%
Other 15 11%
Unknown 17 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2011.
All research outputs
#14,592,319
of 22,653,392 outputs
Outputs from BMC Systems Biology
#595
of 1,142 outputs
Outputs of similar age
#91,381
of 135,895 outputs
Outputs of similar age from BMC Systems Biology
#19
of 41 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,142 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.