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Chronic hyperglycemia is associated with acute kidney injury in patients undergoing CABG surgery – a cohort study

Overview of attention for article published in BMC Cardiovascular Disorders, May 2015
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Title
Chronic hyperglycemia is associated with acute kidney injury in patients undergoing CABG surgery – a cohort study
Published in
BMC Cardiovascular Disorders, May 2015
DOI 10.1186/s12872-015-0028-y
Pubmed ID
Authors

Mehmet Oezkur, Martin Wagner, Dirk Weismann, Jens Holger Krannich, Christoph Schimmer, Christoph Riegler, Victoria Rücker, Rainer Leyh, Peter U. Heuschmann

Abstract

Chronic hyperglycemia (CHG) with HbA1c as an indicator affects postoperative mortality and morbidity after coronary artery bypass grafting surgery (CABG). Acute kidney injury (AKI) is one of the frequent postoperative complications after CABG impacting short-and long-term outcomes. We investigated the association between CHG and postoperative incidence of AKI in CABG patients with and without history of diabetes mellitus (DM). This cohort study consecutively enrolled patients undergoing CABG in 2009 at the department for cardiovascular surgery. CHG was defined as HbA1c ≥ 6.0 %. Patients with advanced chronic kidney disease (CKD) were excluded. The incidence of postoperative AKI and its association with CHG was analyzed by univariate and multivariate logistic regression modeling. Three-hundred-seven patients were analyzed. The incidence of AKI was 48.2 %. Patients with CHG (n = 165) were more likely to be female and had greater waist circumference as well as other comorbid conditions, such as smoking, history of DM, CKD, hypertension, pulmonary hypertension, and chronic obstructive pulmonary disease (all p ≤ 0.05). Preoperative eGFR, atrial fibrillation (AF), history of DM and CHG were associated with an increased risk of postoperative AKI in univariate analyses. In multivariate modelling, history of DM as well as preoperative eGFR and AF lost significance, while age, CHG and prolonged OP duration (p < 0.05) were independently associated with postoperative AKI. Our results suggest that CHG defined on a single measurement of HbA1c ≥ 6.0 % was associated with the incidence of AKI after CABG. This finding might implicate that treatment decisions, including the selection of operative strategies, could be based on HbA1c measurement rather than on a recorded history of diabetes.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 63 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 13%
Student > Ph. D. Student 7 11%
Researcher 7 11%
Student > Master 7 11%
Student > Doctoral Student 4 6%
Other 10 16%
Unknown 20 32%
Readers by discipline Count As %
Medicine and Dentistry 28 44%
Nursing and Health Professions 4 6%
Unspecified 2 3%
Biochemistry, Genetics and Molecular Biology 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 4 6%
Unknown 23 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2016.
All research outputs
#14,225,412
of 22,805,349 outputs
Outputs from BMC Cardiovascular Disorders
#662
of 1,608 outputs
Outputs of similar age
#138,368
of 264,481 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#6
of 16 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,608 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,481 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.