Title |
Snat: a SNP annotation tool for bovine by integrating various sources of genomic information
|
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Published in |
BMC Genomic Data, October 2011
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DOI | 10.1186/1471-2156-12-85 |
Pubmed ID | |
Authors |
Jicai Jiang, Li Jiang, Bin Zhou, Weixuan Fu, Jian-Feng Liu, Qin Zhang |
Abstract |
Most recently, with maturing of bovine genome sequencing and high throughput SNP genotyping technologies, a large number of significant SNPs associated with economic important traits can be identified by genome-wide association studies (GWAS). To further determine true association findings in GWAS, the common strategy is to sift out most promising SNPs for follow-up replication studies. Hence it is crucial to explore the functional significance of the candidate SNPs in order to screen and select the potential functional ones. To systematically prioritize these statistically significant SNPs and facilitate follow-up replication studies, we developed a bovine SNP annotation tool (Snat) based on a web interface. |
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