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Molecular characterization and phylogenetic analysis of transmissible gastroenteritis virus HX strain isolated from China

Overview of attention for article published in BMC Veterinary Research, March 2015
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Title
Molecular characterization and phylogenetic analysis of transmissible gastroenteritis virus HX strain isolated from China
Published in
BMC Veterinary Research, March 2015
DOI 10.1186/s12917-015-0387-8
Pubmed ID
Authors

Xiaoliang Hu, Nannan Li, Zhige Tian, Xin Yin, Liandong Qu, Juanjuan Qu

Abstract

Porcine transmissible gastroenteritis virus (TGEV) is the major etiological agent of viral enteritis and severe diarrhea in suckling piglets. In China, TGEV has caused great economic losses, but its role in epidemic diarrhea is unclear. This study aims to reveal the etiological role of TGEV in piglet diarrhea via molecular characterization and phylogenetic analysis. A TGEV-HX strain was isolated from China, and its complete genome was amplified, cloned, and sequenced. Sequence analysis indicated that it was conserved in the 5' and 3'-non-translated regions, and there were no insertions or deletions in nonstructural genes, such as ORF1a, ORF1b, ORF3a, ORF3b, and ORF7, as well as in genes encoding structural proteins, such as the envelope (E), membrane (M), and nucleoprotein (N) proteins. Furthermore, the phylogenetic analysis indicated that the TGEV-HX strain was more similar to the TGEV Purdue cluster than to the Miller cluster. The present study described the isolation and genetic characterization of a TGEV-HX strain. The detailed analysis of the genetic variation of TGEVs in China provides essential information for further understanding the evolution of TGEVs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 24%
Student > Master 3 14%
Other 2 10%
Student > Bachelor 2 10%
Student > Ph. D. Student 2 10%
Other 3 14%
Unknown 4 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 33%
Veterinary Science and Veterinary Medicine 4 19%
Agricultural and Biological Sciences 2 10%
Nursing and Health Professions 1 5%
Computer Science 1 5%
Other 1 5%
Unknown 5 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2015.
All research outputs
#20,273,512
of 22,805,349 outputs
Outputs from BMC Veterinary Research
#2,417
of 3,050 outputs
Outputs of similar age
#222,498
of 262,802 outputs
Outputs of similar age from BMC Veterinary Research
#36
of 43 outputs
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