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Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications

Overview of attention for article published in Nutrition & Metabolism, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

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11 X users
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Citations

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91 Mendeley
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Title
Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications
Published in
Nutrition & Metabolism, May 2015
DOI 10.1186/s12986-015-0013-6
Pubmed ID
Authors

Zahra Bahadoran, Asghar Ghasemi, Parvin Mirmiran, Fereidoun Azizi, Farzad Hadaegh

Abstract

The ability of inorganic nitrate and nitrite to convert to nitric oxide (NO), and some of its properties e.g. regulation of glucose metabolism, vascular homeostasis, and insulin signaling pathway, have recently raised the hypothesis that inorganic nitrate and nitrite could be potential therapeutic agents in type 2 diabetes. In this review, we reviewed experimental and clinical studies investigating the effect of nitrate/nitrite administration on various aspects of type 2 diabetes. Studies showed that an altered metabolism of nitrate/nitrite and impaired NO pathway occurs in diabetes which could contribute to its complications. Some important beneficial properties, including regulation of glucose homeostasis and insulin signaling pathway, improvement of insulin resistance and vascular function, hypotensive, hypolipidemic as well as anti-inflammatory and anti-oxidative effects have been observed following administration of inorganic nitrate/nitrite. It seems that dietary nitrate/nitrite could be a compensatory fuel for a disrupted nitrate/nitrite/NO pathway and related disorders in diabetes. Although some beneficial properties of nitrate/nitrite have been reported by experimental investigations, long-term clinical studies with various doses of inorganic nitrate/nitrite supplementation, are recommended to confirm these effects.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 90 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 18%
Student > Bachelor 13 14%
Researcher 9 10%
Student > Doctoral Student 7 8%
Other 5 5%
Other 22 24%
Unknown 19 21%
Readers by discipline Count As %
Medicine and Dentistry 23 25%
Biochemistry, Genetics and Molecular Biology 13 14%
Agricultural and Biological Sciences 6 7%
Sports and Recreations 6 7%
Nursing and Health Professions 5 5%
Other 16 18%
Unknown 22 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2023.
All research outputs
#5,395,624
of 25,396,120 outputs
Outputs from Nutrition & Metabolism
#413
of 1,014 outputs
Outputs of similar age
#63,435
of 279,893 outputs
Outputs of similar age from Nutrition & Metabolism
#3
of 9 outputs
Altmetric has tracked 25,396,120 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,014 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,893 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.