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Alternative preparation of propolis extracts: comparison of their composition and biological activities

Overview of attention for article published in BMC Complementary and Alternative Medicine, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)

Mentioned by

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3 tweeters
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3 patents
facebook
1 Facebook page

Citations

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90 Dimensions

Readers on

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265 Mendeley
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Title
Alternative preparation of propolis extracts: comparison of their composition and biological activities
Published in
BMC Complementary and Alternative Medicine, May 2015
DOI 10.1186/s12906-015-0677-5
Pubmed ID
Authors

Loreta Kubiliene, Virginija Laugaliene, Alvydas Pavilonis, Audrius Maruska, Daiva Majiene, Karolina Barcauskaite, Raimondas Kubilius, Giedre Kasparaviciene, Arunas Savickas

Abstract

Propolis is the bee product noted for multiple biological effects, and therefore it is widely used for the prevention and treatment of a variety of diseases. The active substances of propolis are easily soluble in ethanol. However ethanolic extracts cannot be used in treatment of certain diseases encountered in ophthalmology, pediatrics, etc. Unfortunately, the main biologically active substances of propolis are scarcely soluble in water, oil and other solvents usually used in pharmaceutical industry. The aim of this study was to investigate chemical composition, radical scavenging and antimicrobial activity of propolis extracts differently made in nonethanolic solvents. Total content of phenolic compounds in extracts was determined using Folin-Ciocalteu method. Chemical composition and radical scavenging activity of extracts were determined using HPLC system with free radical reaction detector. Antimicrobial activity of examined preparations was evaluated using the agar-well diffusion assay. Total amount of phenolic compounds in extracts made in polyethylene glycol 400 (PEG) and water mixture or in PEG, olive oil and water mixture at 70 °C was comparable to that of ethanolic extract. Predominantly identified compounds were phenolic acids, which contribute ca. 40 % of total radical scavenging activity. Investigated nonethanolic extracts inhibited the growth and reproduction of all tested microrganisms. Antimicrobial activity of some extracts was equal or exceeded the antimicrobial effect of ethanolic extract. Extracts made in pure water or oil only at room temperature, contained more than 5 - 10-fold lower amount of phenolic compounds, and demonstrated no antimicrobial activity. Nonethanolic solvent complex and the effect of higher temperature allows more effective extraction of active compounds from propolis. Concentration of total phenolic compounds in these extracts does not differ significantly from the concentration found in ethanolic extract. Propolis nonethanolic extracts have radical scavenging and antimicrobial activity.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 <1%
Brazil 1 <1%
Unknown 263 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 54 20%
Student > Master 39 15%
Student > Ph. D. Student 29 11%
Researcher 24 9%
Student > Doctoral Student 17 6%
Other 52 20%
Unknown 50 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 23%
Biochemistry, Genetics and Molecular Biology 24 9%
Chemistry 24 9%
Medicine and Dentistry 21 8%
Pharmacology, Toxicology and Pharmaceutical Science 19 7%
Other 54 20%
Unknown 61 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2020.
All research outputs
#2,192,914
of 18,942,198 outputs
Outputs from BMC Complementary and Alternative Medicine
#393
of 2,997 outputs
Outputs of similar age
#33,354
of 244,948 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#1
of 1 outputs
Altmetric has tracked 18,942,198 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,997 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,948 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them