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Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation…

Overview of attention for article published in Journal of Neuroinflammation, October 2011
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1 tweeter

Citations

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36 Mendeley
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Title
Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells
Published in
Journal of Neuroinflammation, October 2011
DOI 10.1186/1742-2094-8-132
Pubmed ID
Authors

Young-Jung Lee, Dong-Young Choi, Im Seup Choi, Jin-Yi Han, Heon-Sang Jeong, Sang Bae Han, Ki-Wan Oh, Jin Tae Hong

Abstract

Amyloidogenesis is linked to neuroinflammation. The tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal, possesses anti-inflammatory properties in cultured macrophages, and in an arthritis animal model. Because astrocytes and microglia are responsible for amyloidogenesis and inflammatory reactions in the brain, we investigated the anti-inflammatory and anti-amyloidogenic effects of 2,4-bis(p-hydroxyphenyl)-2-butenal in lipopolysaccharide (LPS)-stimulated astrocytes and microglial BV-2 cells.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 28%
Student > Ph. D. Student 8 22%
Student > Bachelor 4 11%
Researcher 3 8%
Professor > Associate Professor 2 6%
Other 7 19%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 28%
Biochemistry, Genetics and Molecular Biology 7 19%
Medicine and Dentistry 5 14%
Neuroscience 4 11%
Engineering 2 6%
Other 5 14%
Unknown 3 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2011.
All research outputs
#12,357,523
of 18,796,975 outputs
Outputs from Journal of Neuroinflammation
#1,444
of 2,229 outputs
Outputs of similar age
#76,863
of 114,629 outputs
Outputs of similar age from Journal of Neuroinflammation
#6
of 10 outputs
Altmetric has tracked 18,796,975 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,229 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 114,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.