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Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation…

Overview of attention for article published in Journal of Neuroinflammation, October 2011
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Title
Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells
Published in
Journal of Neuroinflammation, October 2011
DOI 10.1186/1742-2094-8-132
Pubmed ID
Authors

Young-Jung Lee, Dong-Young Choi, Im Seup Choi, Jin-Yi Han, Heon-Sang Jeong, Sang Bae Han, Ki-Wan Oh, Jin Tae Hong

Abstract

Amyloidogenesis is linked to neuroinflammation. The tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal, possesses anti-inflammatory properties in cultured macrophages, and in an arthritis animal model. Because astrocytes and microglia are responsible for amyloidogenesis and inflammatory reactions in the brain, we investigated the anti-inflammatory and anti-amyloidogenic effects of 2,4-bis(p-hydroxyphenyl)-2-butenal in lipopolysaccharide (LPS)-stimulated astrocytes and microglial BV-2 cells.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 42 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 23%
Student > Ph. D. Student 8 19%
Student > Bachelor 6 14%
Researcher 4 9%
Professor > Associate Professor 3 7%
Other 6 14%
Unknown 6 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 26%
Biochemistry, Genetics and Molecular Biology 7 16%
Medicine and Dentistry 6 14%
Neuroscience 4 9%
Nursing and Health Professions 2 5%
Other 7 16%
Unknown 6 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2011.
All research outputs
#15,236,094
of 22,653,392 outputs
Outputs from Journal of Neuroinflammation
#1,727
of 2,601 outputs
Outputs of similar age
#94,146
of 135,640 outputs
Outputs of similar age from Journal of Neuroinflammation
#13
of 19 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,601 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,640 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.