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A terpenoid isolated from sarang semut (Myrmecodia pendans) bulb and its potential for the inhibition and eradication of Streptococcus mutans biofilm

Overview of attention for article published in BMC Complementary Medicine and Therapies, May 2018
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Title
A terpenoid isolated from sarang semut (Myrmecodia pendans) bulb and its potential for the inhibition and eradication of Streptococcus mutans biofilm
Published in
BMC Complementary Medicine and Therapies, May 2018
DOI 10.1186/s12906-018-2213-x
Pubmed ID
Authors

Meirina Gartika, Hening T. Pramesti, Dikdik Kurnia, Mieke H. Satari

Abstract

Dental caries remains a serious problem due to its detrimental effects on individual health and quality of life. The bulbs of Myrmecodia pendans (Merr & Perry), native plants of Papua, have been used as natural remedies for tumours, gout, diarrhoea, and fever. In this study, one of the active compounds of M. pendans was isolated, and its biological activity against the formation of Streptococcus mutans ATCC 25175 biofilm was tested. M. pendans was extracted with ethyl acetate using a Soxhlet apparatus. The extract was then separated, and chromatographic purification provided the isolated compound. The structure of the active compound was then characterized using UV, IR, NMR, and MS spectrometry. The obtained compound was added to S. mutans biofilms to determine the MBIC and MBEC values. The compound isolated from M. pendans was determined to be a labdane diterpene derivative with the formula C31H50O3. The MBIC value of the terpenoid towards the S. mutans biofilms was 50 ppm, and the MBEC value for the 1 min induction time was 40%. The terpenoid extracted from M. pendans has the potential to be developed into an antibacterial agent particularly for preventing the formation of biofilms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 104 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 22 21%
Student > Master 10 10%
Lecturer 7 7%
Student > Postgraduate 6 6%
Student > Ph. D. Student 4 4%
Other 13 13%
Unknown 42 40%
Readers by discipline Count As %
Medicine and Dentistry 23 22%
Pharmacology, Toxicology and Pharmaceutical Science 7 7%
Chemistry 6 6%
Biochemistry, Genetics and Molecular Biology 5 5%
Immunology and Microbiology 4 4%
Other 14 13%
Unknown 45 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2020.
All research outputs
#15,913,483
of 23,628,742 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,073
of 3,710 outputs
Outputs of similar age
#210,405
of 328,475 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#37
of 81 outputs
Altmetric has tracked 23,628,742 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,710 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,475 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.