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MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

Overview of attention for article published in Journal of Hematology & Oncology, May 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users

Citations

dimensions_citation
259 Dimensions

Readers on

mendeley
219 Mendeley
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Title
MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
Published in
Journal of Hematology & Oncology, May 2018
DOI 10.1186/s13045-018-0606-4
Pubmed ID
Authors

Nicola Amodio, Lavinia Raimondi, Giada Juli, Maria Angelica Stamato, Daniele Caracciolo, Pierosandro Tagliaferri, Pierfrancesco Tassone

Abstract

The deeper understanding of non-coding RNAs has recently changed the dogma of molecular biology assuming protein-coding genes as unique functional biological effectors, while non-coding genes as junk material of doubtful significance. In the last decade, an exciting boom of experimental research has brought to light the pivotal biological functions of long non-coding RNAs (lncRNAs), representing more than the half of the whole non-coding transcriptome, along with their dysregulation in many diseases, including cancer.In this review, we summarize the emerging insights on lncRNA expression and functional role in cancer, focusing on the evolutionary conserved and abundantly expressed metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) that currently represents the best characterized lncRNA. Altogether, literature data indicate aberrant expression and dysregulated activity of MALAT1 in human malignancies and envision MALAT1 targeting as a novel treatment strategy against cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 219 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 18%
Researcher 26 12%
Student > Bachelor 25 11%
Student > Master 20 9%
Student > Doctoral Student 12 5%
Other 25 11%
Unknown 72 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 79 36%
Medicine and Dentistry 15 7%
Agricultural and Biological Sciences 8 4%
Neuroscience 7 3%
Immunology and Microbiology 7 3%
Other 28 13%
Unknown 75 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2022.
All research outputs
#3,226,178
of 23,715,461 outputs
Outputs from Journal of Hematology & Oncology
#252
of 1,229 outputs
Outputs of similar age
#65,627
of 329,068 outputs
Outputs of similar age from Journal of Hematology & Oncology
#5
of 32 outputs
Altmetric has tracked 23,715,461 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,229 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,068 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.