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Comparison of methodological quality rating of systematic reviews on neuropathic pain using AMSTAR and R-AMSTAR

Overview of attention for article published in BMC Medical Research Methodology, May 2018
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Title
Comparison of methodological quality rating of systematic reviews on neuropathic pain using AMSTAR and R-AMSTAR
Published in
BMC Medical Research Methodology, May 2018
DOI 10.1186/s12874-018-0493-y
Pubmed ID
Authors

Svjetlana Dosenovic, Antonia Jelicic Kadic, Katarina Vucic, Nikolina Markovina, Dawid Pieper, Livia Puljak

Abstract

Systematic reviews (SRs) in the field of neuropathic pain (NeuP) are increasingly important for decision-making. However, methodological flaws in SRs can reduce the validity of conclusions. Hence, it is important to assess the methodological quality of NeuP SRs critically. Additionally, it remains unclear which assessment tool should be used. We studied the methodological quality of SRs published in the field of NeuP and compared two assessment tools. We systematically searched 5 electronic databases to identify SRs of randomized controlled trials of interventions for NeuP available up to March 2015. Two independent reviewers assessed the methodological quality of the studies using the Assessment of Multiple Systematic Reviews (AMSTAR) and the revised AMSTAR (R-AMSTAR) tools. The scores were converted to percentiles and ranked into 4 grades to allow comparison between the two checklists. Gwet's AC1 coefficient was used for interrater reliability assessment. The 97 included SRs had a wide range of methodological quality scores (AMSTAR median (IQR): 6 (5-8) vs. R-AMSTAR median (IQR): 30 (26-35)). The overall agreement score between the 2 raters was 0.62 (95% CI 0.39-0.86) for AMSTAR and 0.62 (95% CI 0.53-0.70) for R-AMSTAR. The 31 Cochrane systematic reviews (CSRs) were consistently ranked higher than the 66 non-Cochrane systematic reviews (NCSRs). The analysis of individual domains showed the best compliance in a comprehensive literature search (item 3) on both checklists. The results for the domain that was the least compliant differed: conflict of interest (item 11) was the item most poorly reported on AMSTAR vs. publication bias assessment (item 10) on R-AMSTAR. A high positive correlation between the total AMSTAR and R-AMSTAR scores for all SRs, as well as for CSRs and NCSRs, was observed. The methodological quality of analyzed SRs in the field of NeuP was not optimal, and CSRs had a higher quality than NCSRs. Both AMSTAR and R-AMSTAR tools produced comparable quality ratings. Our results point out to weaknesses in the methodology of existing SRs on interventions for the management NeuP and call for future improvement by better adherence to analyzed quality checklists, either AMSTAR or R-AMSTAR.

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Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 14%
Researcher 4 14%
Student > Postgraduate 3 10%
Student > Bachelor 3 10%
Lecturer 2 7%
Other 4 14%
Unknown 9 31%
Readers by discipline Count As %
Medicine and Dentistry 6 21%
Engineering 3 10%
Agricultural and Biological Sciences 1 3%
Computer Science 1 3%
Sports and Recreations 1 3%
Other 3 10%
Unknown 14 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2018.
All research outputs
#20,485,225
of 23,047,237 outputs
Outputs from BMC Medical Research Methodology
#1,892
of 2,030 outputs
Outputs of similar age
#288,401
of 327,709 outputs
Outputs of similar age from BMC Medical Research Methodology
#28
of 28 outputs
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