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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Anti-stress effects of human placenta extract: possible involvement of the oxidative stress system in rats
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, May 2018
|
| DOI | 10.1186/s12906-018-2193-x |
| Pubmed ID | |
| Authors |
Hyun-Jung Park, Hyun Soo Shim, Sunyoung Lee, Dae Hyun Hahm, Hyejung Lee, Chang Taek Oh, Hae Jung Han, Hyi Jeong Ji, Insop Shim |
| Abstract |
Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory and anti-nociceptive activities. However, its mechanisms of stress-induced depression remain unknown. The present study examined the effect of hPH on stress-induced depressive behaviors and biochemical parameters in rats. hPH (0.02 ml, 0.2 ml or 1 ml/rat) was injected intravenously 30 min before the daily stress session in male Sprague-Dawley rats exposed to repeated immobilization stress (4 h/day for 7 days). The depressive-like behaviors of all groups were measured by elevated plus maze (EPM) and forced swimming test (FST). After the behavior tests, brain samples of all groups were collected for the analysis of glutathione peroxidase (GPx) and nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) staining. Treatment with hPH produced a significant decrease of immobility time in the FST compared to the controls. Additionally, hPH treatment elicited a slightly decreasing trend in anxiety behavior on the EPM. Furthermore, hPH increased the level of GPx protein in the hippocampus, and decreased the expression of NADPH-d in the paraventricular nucleus (PVN). This study demonstrated that hPH has anti-stress effects via the regulation of nitric oxide (NO) synthase and antioxidant activity in the brain. These results suggest that hPH may be useful in the treatment of stress-related diseases such as chronic fatigue syndrome. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 46 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 20% |
| Student > Bachelor | 7 | 15% |
| Student > Doctoral Student | 4 | 9% |
| Student > Master | 4 | 9% |
| Student > Ph. D. Student | 2 | 4% |
| Other | 1 | 2% |
| Unknown | 19 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 17% |
| Nursing and Health Professions | 3 | 7% |
| Sports and Recreations | 3 | 7% |
| Chemical Engineering | 1 | 2% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 7 | 15% |
| Unknown | 23 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2023.
All research outputs
#15,291,649
of 23,509,253 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,870
of 3,698 outputs
Outputs of similar age
#199,331
of 328,833 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#30
of 81 outputs
Altmetric has tracked 23,509,253 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,698 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,833 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.