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Systolic characteristics and dynamic changes of the mitral valve in different grades of ischemic mitral regurgitation – insights from 3D transesophageal echocardiography

Overview of attention for article published in BMC Cardiovascular Disorders, May 2018
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

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1 blog

Citations

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16 Mendeley
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Title
Systolic characteristics and dynamic changes of the mitral valve in different grades of ischemic mitral regurgitation – insights from 3D transesophageal echocardiography
Published in
BMC Cardiovascular Disorders, May 2018
DOI 10.1186/s12872-018-0819-z
Pubmed ID
Authors

Caroline Morbach, Diego Bellavia, Stefan Störk, Lissa Sugeng

Abstract

Mitral regurgitation in ischemic heart disease (IMR) is a strong predictor of outcome but until now, pathophysiology is not sufficiently understood and treatment is not satisfying. We aimed to systematically evaluate structural and functional mitral valve leaflet and annular characteristics in patients with IMR to determine the differences in geometric and dynamic changes of the MV between significant and mild IMR. Thirty-seven patients with IMR (18 mild (m)MR, 19 significant (moderate+severe) (s)MR) and 33 controls underwent TEE. 3D volumes were analyzed using 3D feature-tracking software. All IMR patients showed a loss of mitral annular motility and non-planarity, whereas mitral annulus dilation and leaflet enlargement occurred in sMR only. Active-posterior-leaflet-area decreased in early systole in all three groups accompanied by an increase in active-anterior-leaflet-area in early systole in controls and mMR but only in late systole in sMR. In addition to a significant enlargement and loss in motility of the MV annulus, patients with significant IMR showed a spatio-temporal alteration of the mitral valve coaptation line due to a delayed increase in active-anterior-leaflet-area. This abnormality is likely to contribute to IMR severity and is worth the evaluation of becoming a parameter for clinical decision-making. Further, addressing the leaflets aiming to increase the active leaflet-area is a promising therapeutic approach for significant IMR. Additional studies with a larger sample size and post-operative assessment are warranted to further validate our findings and help understand the dynamics of the mitral valve.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 19%
Researcher 3 19%
Student > Doctoral Student 1 6%
Other 1 6%
Student > Ph. D. Student 1 6%
Other 3 19%
Unknown 4 25%
Readers by discipline Count As %
Medicine and Dentistry 6 38%
Engineering 2 13%
Agricultural and Biological Sciences 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Materials Science 1 6%
Other 1 6%
Unknown 4 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2018.
All research outputs
#5,961,944
of 23,052,509 outputs
Outputs from BMC Cardiovascular Disorders
#270
of 1,642 outputs
Outputs of similar age
#103,011
of 326,012 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#7
of 30 outputs
Altmetric has tracked 23,052,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,642 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,012 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.