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Kounis syndrome secondary to amoxicillin/clavulanic acid administration: a case report and review of literature

Overview of attention for article published in BMC Research Notes, March 2015
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Title
Kounis syndrome secondary to amoxicillin/clavulanic acid administration: a case report and review of literature
Published in
BMC Research Notes, March 2015
DOI 10.1186/s13104-015-1072-5
Pubmed ID
Authors

Dissanayake Mudiyanselage Priyantha Ralapanawa, Senanayake Abeysinghe Mudiyanselage Kularatne

Abstract

Kounis syndrome is the concurrence of acute coronary syndromes with mast cells activation induced by hypersensitivity and anaphylactoid insults and is increasingly encountered in clinical practice. The main pathophysiological mechanism is vasospasm of the epicardial coronary arteries due to increased inflammatory mediators that are released during a hypersensitivity reaction. A 74-year -old Sinhalese man with diabetes mellitus was admitted with four day history of high fever with chills and rigors. His urine analysis and blood investigations revealed evidence of urinary tract infection. After excluding allergic conditions, he was given amoxicillin/clavulanic acid intravenously. About 20 minutes after the first dose he felt severe itching of body, nausea , dizziness and sever retrosternal chest pain. Urgent electrocardiogram was taken and it showed widespread ST segment elevations. He was treated for anaphylactic shock as well as acute coronary syndrome and was able to be discharged within a few days. This case highlights the occurrence of acute coronary syndrome following drug induced anaphylaxis. Acute coronary syndrome of this nature may be completely atypical and overlooked. Kounis syndrome should be borne in mind in the event of anaphylactic episode wherein the electrocardiogram becomes essential.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 22%
Other 4 15%
Student > Doctoral Student 2 7%
Student > Bachelor 2 7%
Student > Ph. D. Student 2 7%
Other 2 7%
Unknown 9 33%
Readers by discipline Count As %
Medicine and Dentistry 12 44%
Pharmacology, Toxicology and Pharmaceutical Science 5 19%
Economics, Econometrics and Finance 1 4%
Sports and Recreations 1 4%
Unknown 8 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2015.
All research outputs
#18,416,517
of 22,813,792 outputs
Outputs from BMC Research Notes
#3,015
of 4,262 outputs
Outputs of similar age
#192,642
of 263,386 outputs
Outputs of similar age from BMC Research Notes
#52
of 75 outputs
Altmetric has tracked 22,813,792 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,262 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,386 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.