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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Prognostic role of hormone receptors in endometrial cancer: a systematic review and meta-analysis
|
|---|---|
| Published in |
World Journal of Surgical Oncology, June 2015
|
| DOI | 10.1186/s12957-015-0619-1 |
| Pubmed ID | |
| Authors |
Yanli Zhang, Dong Zhao, Changguo Gong, Fengmei Zhang, Jing He, Wei Zhang, Yulan Zhao, Jing Sun |
| Abstract |
The aim of this study was to summarize the global predicting role of hormone receptors for survival in endometrial cancer. Eligible studies were identified and assessed for quality through multiple search strategies. Data were collected from studies comparing overall survival (OS), cancer-specific survival (CSS), or progression-free survival (PFS) in patients with elevated levels of estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER2) with those in patients with lower levels. The combined hazard ratios of ER, PR, and HER2 for survival were calculated. A total of 98 studies were included for meta-analysis (44 for ER, 38 for PR, and 16 for HER2). Higher levels of either ER or PR could significantly indicate better survival. The pooled hazard ratios (HRs) of ER for OS, CSS, and PFS were 0.75 (95 %CI, 0.68-0.83), 0.45 (95 %CI, 0.33-0.62), and 0.66 (95 %CI, 0.52-0.85), respectively. The combined HRs of PR for OS, CSS, and PFS reached 0.63 (95 %CI, 0.56-0.71), 0.62 (95 %CI, 0.42-0.93), and 0.45 (95 %CI, 0.30-0.68), respectively. In contrast, elevated levels of HER2 could predict worse outcome with a HR of 1.98 (95 %CI, 1.49-2.62) for OS, and a HR of 2.26 (95 %CI, 1.57-3.25) for PFS. In patients with endometrial cancer, higher level of ER and PR predicted favorable survival, and increased level of HER2 was associated with poorer survival. All of the three hormone receptors had prognostic value for survival. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Egypt | 1 | 1% |
| Unknown | 80 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 15% |
| Researcher | 10 | 12% |
| Other | 7 | 9% |
| Student > Postgraduate | 7 | 9% |
| Student > Doctoral Student | 5 | 6% |
| Other | 13 | 16% |
| Unknown | 27 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 34 | 42% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Agricultural and Biological Sciences | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Engineering | 2 | 2% |
| Other | 5 | 6% |
| Unknown | 30 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2022.
All research outputs
#2,373,145
of 22,815,414 outputs
Outputs from World Journal of Surgical Oncology
#34
of 2,043 outputs
Outputs of similar age
#31,905
of 263,904 outputs
Outputs of similar age from World Journal of Surgical Oncology
#2
of 50 outputs
Altmetric has tracked 22,815,414 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,043 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,904 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.