@AbiramEliab We've described this before We thought there was a phototoxic component that could be avoided with bioluminescence See Fig 3 in this 2018 work https://t.co/OxVpm2fFfS But that may not be the case - Fig 5 in this 2022 piece. Both probes ar
@DrChuckSimonton That's the hope - a human cardio model will be a better drug discovery or toxicology platform than current means. We don't know how far down the engineered heart route need to go to get that. Single cell is cheap, simple 3D clusters (eg at
Improving the application of bioluminescence calcium imaging for iPS-CM phenotyping. A collaboration lead by @Lab_Nagai and Nikon. Thanks for including me. https://t.co/OxVpm2fFfS
Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy. https://t.co/6DGPu7DX1E https://t.co/8AznjnCFkq