Title |
From big data analysis to personalized medicine for all: challenges and opportunities
|
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Published in |
BMC Medical Genomics, June 2015
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DOI | 10.1186/s12920-015-0108-y |
Pubmed ID | |
Authors |
Akram Alyass, Michelle Turcotte, David Meyre |
Abstract |
Recent advances in high-throughput technologies have led to the emergence of systems biology as a holistic science to achieve more precise modeling of complex diseases. Many predict the emergence of personalized medicine in the near future. We are, however, moving from two-tiered health systems to a two-tiered personalized medicine. Omics facilities are restricted to affluent regions, and personalized medicine is likely to widen the growing gap in health systems between high and low-income countries. This is mirrored by an increasing lag between our ability to generate and analyze big data. Several bottlenecks slow-down the transition from conventional to personalized medicine: generation of cost-effective high-throughput data; hybrid education and multidisciplinary teams; data storage and processing; data integration and interpretation; and individual and global economic relevance. This review provides an update of important developments in the analysis of big data and forward strategies to accelerate the global transition to personalized medicine. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 5 | 16% |
United States | 3 | 10% |
France | 3 | 10% |
Spain | 2 | 6% |
Germany | 1 | 3% |
Netherlands | 1 | 3% |
Canada | 1 | 3% |
Indonesia | 1 | 3% |
Unknown | 14 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 20 | 65% |
Scientists | 7 | 23% |
Practitioners (doctors, other healthcare professionals) | 3 | 10% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | <1% |
Brazil | 3 | <1% |
Luxembourg | 2 | <1% |
Spain | 2 | <1% |
Canada | 2 | <1% |
Italy | 1 | <1% |
Sweden | 1 | <1% |
France | 1 | <1% |
Indonesia | 1 | <1% |
Other | 2 | <1% |
Unknown | 842 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 154 | 18% |
Researcher | 130 | 15% |
Student > Master | 121 | 14% |
Student > Bachelor | 89 | 10% |
Student > Doctoral Student | 44 | 5% |
Other | 161 | 19% |
Unknown | 161 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 113 | 13% |
Medicine and Dentistry | 113 | 13% |
Computer Science | 107 | 12% |
Agricultural and Biological Sciences | 93 | 11% |
Engineering | 47 | 5% |
Other | 192 | 22% |
Unknown | 195 | 23% |