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Endometrial cancer—how many patients could benefit from sentinel lymph node dissection?

Overview of attention for article published in World Journal of Surgical Oncology, May 2018
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Title
Endometrial cancer—how many patients could benefit from sentinel lymph node dissection?
Published in
World Journal of Surgical Oncology, May 2018
DOI 10.1186/s12957-018-1392-8
Pubmed ID
Authors

Sarah Brugger, Moritz Hamann, Marc Mosner, Michaela Beer, Michael Braun, Martin Pölcher

Abstract

Sentinel lymph node dissection (SLND) may reduce morbidity in patients with endometrial cancer. The objective of this study is to estimate how many systematic lymph node dissections (LND) can be spared with an implementation of a SLN-procedure. Retrospective, single-center study, SLND according to NCCN-Guidelines. In 109 patients of 154 consecutive patients, SLND was performed. The detection rate was 61% on both sides and 86% on at least one side. Classification of uterine risk factors is as follows: low risk 53, intermediate risk 25, high-intermediate risk 13, and high-risk 18. Stage IIIC: 0, 3, 7, 11, respectively. Under the assumption that 56 patients with "higher than low risk" factors would be treated by systematic LND, we spared 26 pelvic and paraaortic LND. After failures of SLN detection, unilateral pelvic LND was performed in 15 patients. Patients with "higher than low risk" factors and node-negative SLN are candidates for a randomized study to prove safety and efficacy. Only every third patient in our study met these criteria. In a cohort of patients with "higher than low risk" endometrial cancer, the implementation of SLND nearly divided the number of radical lymph node dissections in half. Further studies are required to define the best modalities for SLND.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 13%
Student > Postgraduate 4 13%
Student > Doctoral Student 3 10%
Other 3 10%
Student > Master 3 10%
Other 5 16%
Unknown 9 29%
Readers by discipline Count As %
Medicine and Dentistry 17 55%
Biochemistry, Genetics and Molecular Biology 1 3%
Sports and Recreations 1 3%
Nursing and Health Professions 1 3%
Social Sciences 1 3%
Other 1 3%
Unknown 9 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2018.
All research outputs
#18,620,820
of 23,067,276 outputs
Outputs from World Journal of Surgical Oncology
#1,024
of 2,061 outputs
Outputs of similar age
#253,763
of 328,294 outputs
Outputs of similar age from World Journal of Surgical Oncology
#7
of 15 outputs
Altmetric has tracked 23,067,276 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,061 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,294 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.