Title |
Autism risk assessment in siblings of affected children using sex-specific genetic scores
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Published in |
Molecular Autism, October 2011
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DOI | 10.1186/2040-2392-2-17 |
Pubmed ID | |
Authors |
Jerome Carayol, Gerard D Schellenberg, Beth Dombroski, Emmanuelle Genin, Francis Rousseau, Geraldine Dawson |
Abstract |
The inheritance pattern in most cases of autism is complex. The risk of autism is increased in siblings of children with autism and previous studies have indicated that the level of risk can be further identified by the accumulation of multiple susceptibility single nucleotide polymorphisms (SNPs) allowing for the identification of a higher-risk subgroup among siblings. As a result of the sex difference in the prevalence of autism, we explored the potential for identifying sex-specific autism susceptibility SNPs in siblings of children with autism and the ability to develop a sex-specific risk assessment genetic scoring system. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 18% |
Researcher | 9 | 18% |
Student > Bachelor | 7 | 14% |
Other | 4 | 8% |
Student > Doctoral Student | 3 | 6% |
Other | 10 | 20% |
Unknown | 8 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 26% |
Psychology | 10 | 20% |
Agricultural and Biological Sciences | 8 | 16% |
Neuroscience | 4 | 8% |
Social Sciences | 3 | 6% |
Other | 4 | 8% |
Unknown | 8 | 16% |