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An overview of HCV molecular biology, replication and immune responses

Overview of attention for article published in Virology Journal, April 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
patent
1 patent

Citations

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141 Dimensions

Readers on

mendeley
449 Mendeley
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Title
An overview of HCV molecular biology, replication and immune responses
Published in
Virology Journal, April 2011
DOI 10.1186/1743-422x-8-161
Pubmed ID
Authors

Usman A Ashfaq, Tariq Javed, Sidra Rehman, Zafar Nawaz, Sheikh Riazuddin

Abstract

Hepatitis C virus (HCV) causes acute and chronic hepatitis which can eventually lead to permanent liver damage, hepatocellular carcinoma and death. Currently, there is no vaccine available for prevention of HCV infection due to high degree of strain variation. The current treatment of care, Pegylated interferon α in combination with ribavirin is costly, has significant side effects and fails to cure about half of all infections. In this review, we summarize molecular virology, replication and immune responses against HCV and discussed how HCV escape from adaptive and humoral immune responses. This advance knowledge will be helpful for development of vaccine against HCV and discovery of new medicines both from synthetic chemistry and natural sources.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 449 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 <1%
Germany 3 <1%
Netherlands 1 <1%
Brazil 1 <1%
Cameroon 1 <1%
Egypt 1 <1%
Nigeria 1 <1%
China 1 <1%
Spain 1 <1%
Other 1 <1%
Unknown 434 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 101 22%
Student > Bachelor 75 17%
Student > Ph. D. Student 65 14%
Researcher 36 8%
Student > Doctoral Student 24 5%
Other 61 14%
Unknown 87 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 104 23%
Medicine and Dentistry 82 18%
Biochemistry, Genetics and Molecular Biology 73 16%
Immunology and Microbiology 36 8%
Chemistry 16 4%
Other 40 9%
Unknown 98 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2023.
All research outputs
#2,916,087
of 24,387,992 outputs
Outputs from Virology Journal
#267
of 3,246 outputs
Outputs of similar age
#13,181
of 112,578 outputs
Outputs of similar age from Virology Journal
#6
of 50 outputs
Altmetric has tracked 24,387,992 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,246 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 112,578 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.