Title |
Effectiveness of a transdiagnostic individually tailored Internet-based and mobile-supported intervention for the indicated prevention of depression and anxiety (ICare Prevent) in Dutch college students: study protocol for a randomised controlled trial
|
---|---|
Published in |
Trials, February 2018
|
DOI | 10.1186/s13063-018-2477-y |
Pubmed ID | |
Authors |
Felix Bolinski, Annet Kleiboer, Eirini Karyotaki, Judith E. Bosmans, Anna-Carlotta Zarski, Kiona K. Weisel, David D. Ebert, Corinna Jacobi, Pim Cuijpers, Heleen Riper |
Abstract |
Depression and anxiety are common and co-morbid disorders that affect a significant proportion of students. Innovative prevention strategies targeting both conditions are needed to reduce their health burden and costs. ICare Prevent is such an innovative strategy and contains a transdiagnostic individually tailored Internet-based and mobile-supported intervention. It addresses common risk factors of depression and anxiety as part of a large EU-funded multi-country project* (ICare). Little is known about the clinical and cost-effectiveness of this type of intervention compared to care as usual (CAU) for college students. We hypothesize that ICare Prevent will be more (cost-)effective than CAU in the reduction of symptoms of depression and anxiety. A three-arm, parallel, randomized controlled superiority trial will be conducted comparing a guided and an unguided version of ICare Prevent with a control group receiving CAU. The trial will be open-label but outcome assessors will be blinded. A total of 252 college students (age ≥ 16 years) with subclinical symptoms of depression defined as a score ≥ 16 on the Center for Epidemiological Studies Depression Scale (CES-D), and/or anxiety, defined as a score ≥ 5 on the Generalized Anxiety Disorder scale (GAD-7), will be included. Those meeting diagnostic criteria for a depressive or anxiety disorder will be excluded. The primary outcome is change in disorder specific symptom severity from baseline to post-intervention. Secondary endpoints include self-reported depression and anxiety symptoms as well as time to onset of a mood or anxiety disorder until 12-month follow-up. Societal costs and quality of life will be assessed to estimate the intervention's cost-effectiveness compared to CAU. Transdiagnostic individually tailored Internet-based prevention could be a (cost-)effective approach to tackle the disease burden of depression and anxiety among college students. Dutch trial register, NTR 6562 . Registered on 6 July 2017. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 218 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 39 | 18% |
Student > Ph. D. Student | 32 | 15% |
Researcher | 27 | 12% |
Student > Doctoral Student | 21 | 10% |
Student > Bachelor | 12 | 6% |
Other | 28 | 13% |
Unknown | 59 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 81 | 37% |
Medicine and Dentistry | 33 | 15% |
Nursing and Health Professions | 12 | 6% |
Computer Science | 7 | 3% |
Social Sciences | 6 | 3% |
Other | 13 | 6% |
Unknown | 66 | 30% |