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Effect of Xiaoyaosan on major depressive disorder

Overview of attention for article published in Chinese Medicine, July 2015
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3 X users

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Title
Effect of Xiaoyaosan on major depressive disorder
Published in
Chinese Medicine, July 2015
DOI 10.1186/s13020-015-0050-0
Pubmed ID
Authors

Lin-Lin Jing, Xiao-Xia Zhu, Zhi-Ping Lv, Xue-Gang Sun

Abstract

This study aims to evaluate the efficacy of Xiaoyaosan (XYS) for treatment of major depressive disorder (MDD) and to review the studies on antidepressant mechanisms of XYS. The China Knowledge Resource Integrated Database (1998-2014), VIP Journal Integration Platform (1989-2009), and PubMed (1950-2014) were used to search for and collect scientific publications related to XYS and MDD. Clinical trials for "MDD" and "xiaoyao" were screened. Papers that used the original prescription of XYS for treatment and in combination with Western medicines were included, while papers describing modified XYS were excluded. Four investigators read and screened the resulting publications independently, evaluated the associated scientific results and evidence. There were no conclusive results to support the efficacy of XYS for treatment of MDD, owing to limited sample sizes, flaws in blinding and randomization, and lack of multi-centered clinical trials. Among the experimental studies on the effects of XYS possible involvement of 5-hydroxytryptamine, hypothalamic-pituitary-adrenal axis function, and neuroinflammation were possibly involved demonstrated. The effectiveness of XYS for treatment of MDD is uncertain.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 22%
Librarian 3 17%
Student > Ph. D. Student 2 11%
Student > Doctoral Student 1 6%
Unknown 8 44%
Readers by discipline Count As %
Medicine and Dentistry 4 22%
Nursing and Health Professions 2 11%
Psychology 2 11%
Agricultural and Biological Sciences 1 6%
Chemical Engineering 1 6%
Other 1 6%
Unknown 7 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2015.
All research outputs
#15,517,312
of 25,373,627 outputs
Outputs from Chinese Medicine
#240
of 660 outputs
Outputs of similar age
#137,741
of 275,149 outputs
Outputs of similar age from Chinese Medicine
#2
of 7 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 660 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,149 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.