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Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

Overview of attention for article published in BMC Genomics, November 2010
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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2 X users
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2 patents

Citations

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347 Dimensions

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319 Mendeley
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Title
Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish
Published in
BMC Genomics, November 2010
DOI 10.1186/1471-2164-11-643
Pubmed ID
Authors

Jared V Goldstone, Andrew G McArthur, Akira Kubota, Juliano Zanette, Thiago Parente, Maria E Jönsson, David R Nelson, John J Stegeman

Abstract

Increasing use of zebrafish in drug discovery and mechanistic toxicology demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP enzymes catalyze oxidative transformation leading to activation or inactivation of many endogenous and exogenous chemicals, with consequences for normal physiology and disease processes. Many CYPs potentially have roles in developmental specification, and many chemicals that cause developmental abnormalities are substrates for CYPs. Here we identify and annotate the full suite of CYP genes in zebrafish, compare these to the human CYP gene complement, and determine the expression of CYP genes during normal development.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 319 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 2%
United States 4 1%
Brazil 3 <1%
Canada 1 <1%
Germany 1 <1%
Spain 1 <1%
Belgium 1 <1%
Unknown 303 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 69 22%
Researcher 54 17%
Student > Master 52 16%
Student > Bachelor 31 10%
Professor > Associate Professor 16 5%
Other 45 14%
Unknown 52 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 99 31%
Biochemistry, Genetics and Molecular Biology 38 12%
Pharmacology, Toxicology and Pharmaceutical Science 34 11%
Environmental Science 29 9%
Medicine and Dentistry 17 5%
Other 38 12%
Unknown 64 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2022.
All research outputs
#4,052,870
of 22,957,478 outputs
Outputs from BMC Genomics
#1,657
of 10,686 outputs
Outputs of similar age
#26,503
of 180,913 outputs
Outputs of similar age from BMC Genomics
#16
of 83 outputs
Altmetric has tracked 22,957,478 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,686 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,913 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.