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Mendeley readers
Attention Score in Context
| Title |
Polypharmacy among HIV positive older adults on anti-retroviral therapy attending an urban clinic in Uganda
|
|---|---|
| Published in |
BMC Geriatrics, May 2018
|
| DOI | 10.1186/s12877-018-0817-0 |
| Pubmed ID | |
| Authors |
Michael Ssonko, Fiona Stanaway, Harriet K. Mayanja, Tabitha Namuleme, Robert Cumming, John L. Kyalimpa, Yvonne Karamagi, Barbara Mukasa, Vasi Naganathan |
| Abstract |
Polypharmacy has not been investigated in patients living with HIV in developing countries. The aims of this study were to determine the prevalence of polypharmacy, the factors associated with polypharmacy and whether polypharmacy was associated with adverse effects among older adults on anti-retroviral therapy (ART). Cross-sectional study in older adults aged 50 and over on ART attending an outpatient HIV/AIDS care centre in Uganda. Demographic and clinical data collected on number and type of medications plus supplements, possible medication related side-effects, comorbidity, frailty, cognitive impairment, current CD4 count and viral load. Of 411 participants, 63 (15.3, 95% C.I. 11.9, 18.8) had polypharmacy (≥ 4 non- HIV medications). In multivariate analyses, polypharmacy was associated with one or more hospitalisations in the last year (Prevalence Ratio PR = 1.8, 95% C.I. 1.1, 3.1, p = 0.02), prescription by an internist (PR = 3.6, 95% C.I. 1.3, 10.5, p = 0.02) and frailty index scores of 5 to 6 (PR = 10.6, 95% C.I. 1.4, 78, p = 0.02), and 7 or more (PR = 17.4, 95% C.I. 2.4, 126.5, p = 0.005). Polypharmacy was not associated with frequency and severity of possible medication related side effects and falls. Polypharmacy is common among older HIV infected patients in sub-Saharan Africa. It's more prevalent among frail people, who have been in hospital in the last year and who have been seen by an internist. We found no evidence that polypharmacy results in any harm but this is worth exploring further. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 111 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 14% |
| Student > Ph. D. Student | 11 | 10% |
| Researcher | 8 | 7% |
| Lecturer | 7 | 6% |
| Student > Bachelor | 7 | 6% |
| Other | 23 | 21% |
| Unknown | 39 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 25% |
| Nursing and Health Professions | 12 | 11% |
| Social Sciences | 5 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Immunology and Microbiology | 3 | 3% |
| Other | 15 | 14% |
| Unknown | 43 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#20,514,440
of 23,081,466 outputs
Outputs from BMC Geriatrics
#2,915
of 3,261 outputs
Outputs of similar age
#290,603
of 331,250 outputs
Outputs of similar age from BMC Geriatrics
#58
of 58 outputs
Altmetric has tracked 23,081,466 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,261 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,250 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.