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Mendeley readers
Attention Score in Context
| Title |
Taurine: the appeal of a safe amino acid for skeletal muscle disorders
|
|---|---|
| Published in |
Journal of Translational Medicine, July 2015
|
| DOI | 10.1186/s12967-015-0610-1 |
| Pubmed ID | |
| Authors |
Annamaria De Luca, Sabata Pierno, Diana Conte Camerino |
| Abstract |
Taurine is a natural amino acid present as free form in many mammalian tissues and in particular in skeletal muscle. Taurine exerts many physiological functions, including membrane stabilization, osmoregulation and cytoprotective effects, antioxidant and anti-inflammatory actions as well as modulation of intracellular calcium concentration and ion channel function. In addition taurine may control muscle metabolism and gene expression, through yet unclear mechanisms. This review summarizes the effects of taurine on specific muscle targets and pathways as well as its therapeutic potential to restore skeletal muscle function and performance in various pathological conditions. Evidences support the link between alteration of intracellular taurine level in skeletal muscle and different pathophysiological conditions, such as disuse-induced muscle atrophy, muscular dystrophy and/or senescence, reinforcing the interest towards its exogenous supplementation. In addition, taurine treatment can be beneficial to reduce sarcolemmal hyper-excitability in myotonia-related syndromes. Although further studies are necessary to fill the gaps between animals and humans, the benefit of the amino acid appears to be due to its multiple actions on cellular functions while toxicity seems relatively low. Human clinical trials using taurine in various pathologies such as diabetes, cardiovascular and neurological disorders have been performed and may represent a guide-line for designing specific studies in patients of neuromuscular diseases. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 20% |
| Germany | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 2 | 1% |
| Brazil | 1 | <1% |
| Unknown | 158 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 26 | 16% |
| Researcher | 24 | 15% |
| Student > Ph. D. Student | 19 | 12% |
| Student > Master | 19 | 12% |
| Other | 10 | 6% |
| Other | 31 | 19% |
| Unknown | 32 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 19% |
| Agricultural and Biological Sciences | 24 | 15% |
| Biochemistry, Genetics and Molecular Biology | 14 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 7% |
| Nursing and Health Professions | 9 | 6% |
| Other | 33 | 20% |
| Unknown | 40 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 87. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2023.
All research outputs
#483,439
of 25,263,619 outputs
Outputs from Journal of Translational Medicine
#102
of 4,603 outputs
Outputs of similar age
#5,382
of 269,548 outputs
Outputs of similar age from Journal of Translational Medicine
#1
of 106 outputs
Altmetric has tracked 25,263,619 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,603 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,548 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.